Abstract
Purpose
To clarify the relationship between aseptic loosening of hip arthroplasty and adhesion molecules on interfacial membrane from revisional hip arthroplasty.
Materials and Methods
We studied 26 revisional total hip arthroplasties between May 2004 and July 2006, and 15 synovial tissues from hip fractures were selected as the control group. We analyzed the degree of femoral osteolysis by Paprosky's classification. We examined the expression of soluble endothelial leukocyte adhesion molecule-1 (E-selectin), vascular adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1) by immunohistochemical staining technique. We compared and analyzed radiologic evaluation and expression of adhesion molecules.
Figures and Tables
References
1. Al-Saffar N, Mah JT, Kadoya Y, Revell PA. Neovascularisation and the induction of cell adhesion molecules in response to degradation products from orthopaedic implants. Ann Rheum Dis. 1995. 54:201–208.
2. Amstutz HC, Campbell P, Kossovsky N, Clarke IC. Mechanism and clinical significance of wear debris-induced osteolysis. Clin Orthop Relat Res. 1992. 276:7–18.
3. Betts F, Wright T, Salvati EA, Boskey A, Bansal M. Cobalt-alloy metal debris in periarticular tissues from total hip revision arthroplasties. Metal contents and associated histologic findings. Clin Orthop Relat Res. 1992. 276:75–82.
4. Chiba J, Rubash HE, Kim KJ, Iwaki Y. The characterization of cytokines in the interface tissue obtained from failed cementless total hip arthroplasty with and without femoral osteolysis. Clin Orthop Relat Res. 1994. 300:304–312.
5. Cicuttini FM, Martin M, Boyd AW. Cytokine induction of adhesion molecules on synovial type B cells. J Rheumatol. 1994. 21:406–412.
6. Cila E, Alpaslan AM, Melli M, Tokgözoğlu AM. Prostaglandin E2 activity in the synovial-like membrane. J Arthroplasty. 1994. 9:67–71.
7. Fairburn K, Kunaver M, Wilkinson LS, Cambridge G, Haskard D, Edwards JC. Intercellular adhesion molecules in normal synovium. Br J Rheumatol. 1993. 32:302–306.
8. Fassbender K, Kaptur S, Becker P, Groschl J, Hennerici M. Adhesion molecules in tissue injury: kinetics of expression and shedding and association with cytokine release in humans. Clin Immunol Immunopathol. 1998. 89:54–60.
9. Freeman MA, Bradley GW, Revell PA. Observations upon the interface between bone and polymethylmethacrylate cement. J Bone Joint Surg Br. 1982. 64:489–493.
10. Griffiths CE, Barker JN, Kunkel S, Nickoloff BJ. Modulation of leucocyte adhesion molecules, a T-cell chemotaxin (IL-8) and a regulatory cytokine (TNF-alpha) in allergic contact dermatitis (rhus dermatitis). Br J Dermatol. 1991. 124:519–526.
11. Hale LP, Martin ME, McCollum DE, et al. Immunohistologic analysis of the distribution of cell adhesion molecules within the inflammatory synovial microenvironment. Arthritis Rheum. 1989. 32:22–30.
12. Harris WH, Schiller AL, Scholler JM, Freiberg RA, Scott R. Extensive localized bone resorption in the femur following total hip replacement. J Bone Joint Surg Am. 1976. 58:612–618.
13. Jasty MJ, Floyd WE 3rd, Schiller AL, Goldring SR, Harris WH. Localized osteolysis in stable, non-septic total hip replacement. J Bone Joint Surg Am. 1986. 68:912–919.
14. Jiranek WA, Machado M, Jasty M, et al. Production of cytokines around loosened cemented acetabular components. Analysis with immunohistochemical techniques and in situ hybridization. J Bone Joint Surg Am. 1993. 75:863–879.
15. Johanson NA, Bullough PG, Wilson PD Jr, Salvati EA, Ranawat CS. The microscopic anatomy of the bone-cement interface in failed total hip arthroplasties. Clin Orthop Relat Res. 1987. 218:123–135.
16. Jones LC, Frondoza C, Hungerford DS. Immunohistochemical evaluation of interface membranes from failed cemented and uncemented acetabular components. J Biomed Mater Res. 1999. 48:889–898.
17. Koch AE, Burrows JC, Haines GK, Carlos TM, Harlan JM, Leibovich SJ. Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues. Lab Invest. 1991. 64:313–320.
18. Norris P, Poston RN, Thomas DS, Thornhill M, Hawk J, Haskard DO. The expression of endothelial leukocyte adhesion molecule-1 (ELAM-1), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in experimental cutaneous inflammation: a comparison of ultraviolet B erythema and delayed hypersensitivity. J Invest Dermatol. 1991. 96:763–770.
19. Paprosky WG, Perona PG, Lawrence JM. Acetabular defect classification and surgical reconstruction in revision arthroplasty. A 6-year follow-up evaluation. J Arthroplasty. 1994. 9:33–44.
20. Sabokbar A, Fujikawa Y, Neale S, Murray DW, Athanasou NA. Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells. Ann Rheum Dis. 1997. 56:414–420.
21. Shimada H, Eguchi K, Ueki Y, et al. Interleukin 4 increases human synovial cell expression of VCAM-1 and T cell binding. Ann Rheum Dis. 1994. 53:601–607.
22. van Dinther-Janssen AC, Kraal G, van Soesbergen RM, Scheper RJ, Meijer CJ. Immunohistological and functional analysis of adhesion molecule expression in the rheumatoid synovial lining layer. Implications for synovial lining cell destruction. J Rheumatol. 1994. 21:1998–2004.
23. Wilkinson LS, Edwards JC, Poston RN, Haskard DO. Expression of vascular cell adhesion molecule-1 in normal and inflamed synovium. Lab Invest. 1993. 68:82–88.