There are a few reports of femoral neuropathy caused by an iliopsoas hematoma combined with trauma, hemophilia, and anticoagulation therapy. There is some debate as to whether conservative treatment or surgical management is the treatment of choice for femoral neuropathy. In some cases, surgical management is used to minimize the level of nerve damage and for better functional recovery. We report a case of femoral neuropathy on the other side of a total hip replacement arthroplasty (THRA) caused by an iliopsoas hematoma during heparin anticoagulation therapy.