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| J Korean Orthop Assoc. 2005 Dec;40(7):977-983. Korean. Published online December 27, 2017. https://doi.org/10.4055/jkoa.2005.40.7.977 | |
| Copyright © 2005 The Korean Orthopaedic Association | |
Byung Sung Kim,
Moon Sang Chung,*
Won Sik Choy,†
and Goo Hyun Baek *
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| Department of Orthopaedic Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea. | |
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*Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul, Korea. | |
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†Department of Orthopaedic Surgery, Eulji University College of Medicine, Daejeon, Korea. | |
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Abstract
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Purpose
The aim of this study was to evaluate the effect of modified end-to-side neurorrhaphy on functional recovery, by modulating the epineurial window and contact areas with a donor nerve, using a rat median nerve and finger flexors.
Materials and Methods
Four experimental groups (n=10) were used: a large epineurial window and a spiral circumferential contact with the donor nerve (Group A): a large epineurial window and half a contact with the donor nerve (Group B): a small epineurial window and half a contact with the donor nerve (Group C): and a nontransferred control (Group D). Grasping testing, muscle contractility testing, and a histological study were performed.
Results
Twenty weeks after surgery, the grasping strength, tetanic force and nerve fiber count were significantly higher in group A than group C. The modified end-to-side repair can enhance axonal sprouting from an intact nerve, and improve functional recovery.
Conclusion
Either the epineurial window surface area or the contact configuration with the donor nerve is an important factor in an end-to-side coaptation model. |
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Keywords: Peripheral nerve injury; Epineurial window area; Contact area with donor nerve; Nerve regeneration |
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