Recently, the use of acupuncture has been increasing for the management of low back pain and herniated nucleus pulposus. There are many debates on its usefulness and associated complications. Complications such as hemorrhage, infection, direct internal organ or nerve injury and disease transmission have been reported. We report a case of dural sac and nerve root compression caused by chronic inflammatory granuloma. This chronic inflammatory granuloma, which might have been formed by local hemorrhage or low-grade infection after acupuncture is highly suspected to produce the symptoms of spinal stenosis; moreover, after surgical excision of the granuloma the patient's symptoms were eliminated. Hence, we report this case and discuss the possibility of the acupuncture as a cause.