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Lee, Kim, Kang, Choi, and Lee: Clinical Experience of 3T Breast MRI in Detecting the Additional Lesions in Breast Cancer Patients
Original Article
Journal of the Korean Society of Magnetic Resonance in Medicine

Journal of the Korean Society of Magnetic Resonance in Medicine 2010; 14(2): 121-125.

Published online: 31 December 2010

DOI: https://doi.org/10.13104/jksmrm.2010.14.2.121

Clinical Experience of 3T Breast MRI in Detecting the Additional Lesions in Breast Cancer Patients

Ji Hye Lee1, Sung Hun Kim1, Bong Joo Kang1, Jae Jeong Choi1, Ah Won Lee2

1Department of Radiology, College of Medicine, The Catholic University of Korea, Korea.

2Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Korea.

Address reprint requests to: Sung Hun Kim, M.D., Departement of Radiology, The Catholic University of Korea, 505, Banpo-dong, Seocho-gu, Seoul 137-701, Korea. Tel. 82-2-2258-6250, Fax. 82-2-2258-1457, rad-ksh@catholic.ac.kr

Received 9 June 2010       Revised 15 September 2010       Accepted 17 November 2010

Copyright © 2010 Korean Society of Magnetic Resonance in Medicine

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study was to evaluate the diagnostic accuracy of 3.0-T breast MRI for detecting additional breast cancer soon after the initial diagnosis of breast cancer.

Materials and Methods

From March to June 2009, 101 patients recently diagnosed breast cancer underwent breast MRI and surgery. Parameters analyzed on MRI were total extent of tumor, suspicious findings of multifocal, multicentric, or contralateral cancer. The diagnosis of MRI-detected cancer was confirmed by means of biopsy or surgical specimen evaluation after the localization.

Results

MRI showed 37 additional suspicious findings in 34 patients. Twenty nine findings were true-positive (29/37, 78.4%), including 16 cases of multifocality, 11 cases of multicentricity and 2 cases of contralateral cancer. Among these cancers, 13 (44.8%) were ductal carcinoma in situ (DCIS) and 16 (55.1%) were infiltrating cancer. Eight findings were false-positive (8/37, 21.6%) including 6 cases of benign disease and 2 cases of high-risk lesions.

Conclusion

In women with recently diagnosed breast cancer, 3.0-T MR imaging showed additional suspicious findings in 33.7%. The sensitivity and specificity for detecting additional breast cancer was 100% and 89.3%, respectively.

Keywords: Magnetic resonance imaging, 3.0 Tesla, Breast, Breast cancer

Figures and Tables

Fig. 1
35-year-old woman with invasive ductal cancer and true positive multifocal malignancies. 3D MIP image shows an index mass (arrow) and two multifocal daughter nodules (arrowheads) at upper outer quadrant of right breast.
jksmrm-14-121-g001
Fig. 2
53-year-old woman with invasive ductal cancer and true positive multicentric malignancies. Axial subtraction image shows an index mass (arrow) at upper inner quadrant of left breast. Also detected multifocal and multicentric malignancies (arrowheads) are noted at left upper breast.
jksmrm-14-121-g002
Fig. 3
63-year-old woman with invasive ductal cancer and true positive contralateral malignancy. Axial subtraction image shows an index mass at right breast and an irregular spiculated homogeneously enhancing mass at left breast.
jksmrm-14-121-g003
Table 1
Additional Suspicious Lesions on 3.0 T MRI
jksmrm-14-121-i001

Note.-DCIS indicates ductal carcinoma in situ.

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