Journal List > J Korean Surg Soc > v.78(2) > 1011075

Park, Kim, and Cho: Thyroid Hemiagenesis Associated with Micropapillary Thyroid Carcinoma

Abstract

Thyroid hemiagenesis of one lobe of the thyroid is a rare congenital anomaly in which one lobe of the thyroid gland fails to develop. It is more frequently found in women than in men, and absence of the left lobe is more common. The variations of prevalence of the anomaly have been reported to be around 0.05~0.2%. Patients with thyroid hemiagenesis are usually asymptomatic and discovered incidentally with other pathologic condition such as a benign adenoma, multinodular goiter, hyperthyroidism or carcinomas. We report a 29-year-old woman with an incidentally discovered hemiagenesis of the right thyroid.

Figures and Tables

Fig. 1
Computed tomography showing hemiagenesis of the right thyroid and left-sided thyroid nodules (arrow).
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Fig. 2
Specimen after removal of left thyroid lobe.
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Fig. 3
Histologic examination of the nodule reveal focal papillary adenocarcinoma with intranuclear inclusion, groove and ground glass nuclei (H&E stain, ×40).
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References

1. Henle J. Handbuch der Systematischen Anatomie des Menschen. 1866. Vol. 2. Braunschweig: Vieweg;538.
2. Korpal-Szczyrska M, Kosiak W, Swieton D. Prevalence of thyroid hemiagenesis in an asymptomatic schoolchildren population. Thyroid. 2008. 18:637–639.
3. Maiorana R, Carta A, Floriddia G, Leonardi D, Buscema M, Sava L, et al. Thyroid hemiagenesis: prevalence in normal children and effect on thyroid function. J Clin Endocrinol Metab. 2003. 88:1534–1536.
4. Khatri VP, Espinosa MH, Harada WA. Papillary adenocarcinoma in thyroid hemiagenesis. Head Neck. 1992. 14:312–315.
5. Kim MR, Chung CH, Lim SK, Kim KR, Lee HC, Hur KB. A case of thyroid hemiagenesis with primary myxedema. J Korean Soc Endocrinol. 1990. 5:149–154.
6. Gursoy A, Anil C, Unal AD, Demirer AN, Tutuncu NB, Erdogan MF. Clinical and epidemiological characteristics of thyroid hemiagenesis: ultrasound screening in patients with thyroid disease and normal population. Endocrine. 2008. 33:338–341.
7. Shaha AR, Gujarati R. Thyroid hemiagenesis. J Surg Oncol. 1997. 65:137–140.
8. Harada T, Nishikawa Y, Ito K. Aplasia of one thyroid lobe. Am J Surg. 1972. 124:617–619.
9. Mortimer PS, Tomlinson IW, Rosenthal FD. Hemiaplasia of the thyroid with thyrotoxicosis. J Clin Endocrinol Metab. 1981. 52:152–155.
10. Piera J, Garriga J, Calabuig R, Bargallo D. Thyroidal hemiagenesis. Am J Surg. 1986. 151:419–421.
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