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Park, Bae, Kim, Kim, and Song: Annual Change of Clinicopathologic Characteristics after Radical Gastrectomy due to Gastric Cancer
Original Article
Journal of the Korean Surgical Society

Journal of the Korean Surgical Society 2009; 77(2): 88-95.

Published online: 4 August 2009

DOI: https://doi.org/10.4174/jkss.2009.77.2.88

Annual Change of Clinicopathologic Characteristics after Radical Gastrectomy due to Gastric Cancer

Man Woo Park, M.D., Jung Min Bae, M.D., Se Won Kim, M.D., Sang Woon Kim, M.D., Sun Kyo Song, M.D.

Department of Surgery, Yeungnam University College of Medicine, Daegu, Korea.

Corresponding author (swkim@med.yu.ac.kr)

Received 8 March 2009       Accepted 25 May 2009

Copyright © 2009 The Korean Surgical Society

Abstract

Purpose

Recently, early gastric cancer has increased in Korea. Thus, endoscopic treatment and laparoscopic gastrectomy has increased in early gastric cancer patients. We studied periodic change and characteristics in gastric cancer patients. Thus, we analyzed annual change of clinicopathological characteristics and long-term survival results of gastric cancer patients after radical gastrectomy over 10 years.

Methods

From 1995 to 2004, 2,387 patients underwent radical gastrectomy due to gastric cancer. We analyzed annual characteristics, sex, age distribution, cancer location, depth of invasion, lymph node metastasis, UICC stage and 5-year survival rates, retrospectively from medical records.

Results

The number of gastric cancer patient has increased annually. The ratio of male to female was 2:1. Gastric cancer was most common and increased annually in the 60~79-year age group. Early gastric cancer increased annually. The 5-year survival rate was 93% in stage Ia, 89% in stage Ib, 72% in stage II, 51% in stage IIIA, 38% in stage IIIb and 22% in stage IV. Multivariate analysis revealed that UICC stage (or depth of invasion and lymph node metastasis) and cancer location were the main independent prognostic factors.

Conclusion

Prognosis is improved due to increase of early gastric cancer. So, we should attempt diagnosis early and treat early gastric cancer. Active treatment is recommended even for the elderly gastric cancer patients. And care should be taken with respect to morbidity and mortality.

Keywords: Gastric cancer, Gastrectomy, Clinicopathological characteristics

Figures and Tables

Fig. 1
Annual change of patients and sex proportion.
jkss-77-88-g001
Fig. 2
Annual change according to age group.
jkss-77-88-g002
Fig. 3
Annual change according to tumor location.
jkss-77-88-g003
Fig. 4
Annual change according to operation type.
jkss-77-88-g004
Fig. 5
Annual change according to Lauren classification.
jkss-77-88-g005
Fig. 6
Annual change according to cell differentiation.
jkss-77-88-g006
Fig. 7
Annual change according to EGC and AGC.
jkss-77-88-g007
Fig. 8
Annual change according to depth of invasion.
jkss-77-88-g008
Fig. 9
Annual change according to lymph node metastasis.
jkss-77-88-g009
Fig. 10
Annual change according to UICC stage.
jkss-77-88-g010
Table 1
Clinicopathological characteristics and survival rate
jkss-77-88-i001
Table 2
Multivariate analysis according to Cox proportional hazard model
jkss-77-88-i002

*Exp (B) = relative risk

Table 3
The comparison of EGC vs AGC according to age group
jkss-77-88-i003
Table 4
Comparison of 5 year survival rate between previously published data and our data
jkss-77-88-i004
Table 5
The difference of advance state according to cancer location
jkss-77-88-i005

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