Journal List > J Korean Surg Soc > v.77(6) > 1011044

So and Byun: Usefulness of PTFE Graft in Above-Knee Femoropopliteal Artery Bypass

Abstract

Purpose

Which graft material is appropriate for the above-knee femoropopliteal (AK fem-pop) bypass has been a controversy. We were to evaluate the usefulness of PTFE graft in AK fem-pop bypass by comparing the results of autogenous vein graft in below-knee femoropopliteal bypass.

Methods

This was a retrospective study of data for Fem-Pop bypass from August 1999 to August 2008. The median follow-up was 59.9±27.3 months. The demographic data, patency rate, secondary procedures, and amputation rate were compared, and statistical comparison was performed by Kaplan-Meier method, Log-rank test, and Chi-square test.

Results

Seventy-three bypasses were performed in 63 patients: PTFE graft in 48 cases (Group A), autogenous vein in 25 cases (Group B). Sixty-one patients (96.81%) were men. The mean age was 67.3±8.0 years. The indication for surgery was intermittent claudication in 27 cases (37.0%), critical limb in 46 cases (63.0%). The 6-yr primary patency rates were 28.1%; 60.3%, the 6-yr secondary patency rates were 37.2±8.4%, 67.0±14.7% in Group A and Group B, respectively (P<0.05). The number of secondary procedures was 31 and 3, respectively (P<0.05). Major amputation at later periods was not needed in Group B, but there were 9 cases in group A (P<0.05).

Conclusion

PTFE graft for above-knee femoropopliteal bypass shows poor long-term patency with a large number of secondary procedures and a higher amputation rate than vein graft in BK Fem-Pop bypass. PTFE graft should be limited to patients with high operative risk, or poor venous graft.

Figures and Tables

Table 1
Comparison of clinical characteristics
jkss-77-410-i001
Table 2
Comparison of primary cumulative patency rates
jkss-77-410-i002

Kaplan-Meier method; Mean±SE.

Table 3
Comparison of secondary cumulative patency rates
jkss-77-410-i003

Kaplan-Meier method; Mean±SE.

Table 4
Frequency of secondary procedures for failing and failed graft
jkss-77-410-i004

*Others = angioplasty with/without stent, angioplasty, graft extension (P<0.01).

Table 5
Amputation incidence according to time, extend, and operation indication
jkss-77-410-i005

*DC = disabling claudication; CLI = critical limb ischemia.

References

1. Sala F, Hassen-Khodja R, Lecis A, Bouillanne PJ, Declemy S, Batt M. Long-term outcome of femoral above-knee popliteal artery bypass using autologous saphenous vein versus expanded polytetrafluoroethylene grafts. Ann Vasc Surg. 2003. 17:401–407.
2. Burger DH, Kappetein AP, Van Bockel JH, Breslau PJ. A prospective randomized trial comparing vein with polytetrafluoroethylene in above-knee femoropopliteal bypass grafting. J Vasc Surg. 2000. 32:278–283.
3. Johnson WC, Williford WO. Benefits, morbidity, and mortality associated with long-term administration of oral anticoagulant therapy to patients with peripheral arterial bypass procedures: a prospective randomized study. J Vasc Surg. 2002. 35:413–421.
4. Klinkert P, Schepers A, Burger DH, van Bockel JH, Breslau PJ. Vein versus polytetrafluoroethylene in above-knee femoropopliteal bypass grafting: five-year results of a randomized controlled trial. J Vasc Surg. 2003. 37:149–155.
5. Albers M, Romiti M, Brochado-Neto FC, Pereira CA. Metaanalysis of alternate autologous vein bypass grafts to infrapopliteal arteries. J Vasc Surg. 2005. 42:449–455.
6. Rosen RC, Johnson WC, Bush HL Jr, Cho SI, O'Hara ET, Nabseth DC. Staged infrainguinal revascularization: initial prosthetic above-knee bypass followed by a distal vein bypass for recurrent ischemia. A valid concept for extending limb salvage? Am J Surg. 1986. 152:224–230.
7. Veith FJ, Gupta SK, Ascer E, White-Flores S, Samson RH, Scher LA, et al. Six-year prospective multicenter randomized comparison of autologous saphenous vein and expanded polytetrafluoroethylene grafts in infrainguinal arterial reconstructions. J Vasc Surg. 1986. 3:104–114.
8. Sterpetti AV, Schultz RD, Feldhaus RJ, Peetz DJ Jr. Seven-year experience with polytetrafluoroethylene as above-knee femoropopliteal bypass graft. Is is worthwhile to preserve the autologous saphenous vein? J Vasc Surg. 1985. 2:907–912.
9. Kim JY, Kim YW, Huh S, Nah MC. Comparison of surgical outcomes between reversed vein graft and prosthetic graft in above-knee femoropopliteal bypass. J Korean Soc Vasc Surg. 2002. 18:68–75.
10. AbuRahma AF, Robinson PA, Holt SM. Prospective controlled study of polytetrafluoroethylene versus saphenous vein in claudicant patients with bilateral above knee femoropopliteal bypasses. Surgery. 1999. 126:594–602.
11. Allen BT, Reilly JM, Rubin BG, Thompson RW, Anderson CB, Flye MW, et al. Femoropopliteal bypass for claudication: vein vs. PTFE. Ann Vasc Surg. 1996. 10:178–185.
12. Poletti LF, Matsuura JH, Dattilo JB, Posner MP, Lee HM, Scouvart M, et al. Should vein be saved for future operations? A 15-year review of infrainguinal bypasses and the subsequent need for autogenous vein. Ann Vasc Surg. 1998. 12:143–147.
13. Green RM, McNamara J, Ouriel K, DeWeese JA. Comparison of infrainguinal graft surveillance techniques. J Vasc Surg. 1990. 11:207–215.
14. Johnson WC, Lee KK. A comparative evaluation of polytetrafluoroethylene, umbilical vein, and saphenous vein bypass grafts for femoral-popliteal above-knee revascularization: a prospective randomized Department of Veterans Affairs cooperative study. J Vasc Surg. 2000. 32:268–277.
15. Klinkert P, Post PN, Breslau PJ, van Bockel JH. Saphenous vein versus PTFE for above-knee femoropopliteal bypass. A review of the literature. Eur J Vasc Endovasc Surg. 2004. 27:357–362.
16. Sarac TP, Huber TS, Back MR, Ozaki CK, Carlton LM, Flynn TC, et al. Warfarin improves the outcome of infrainguinal vein bypass grafting at high risk for failure. J Vasc Surg. 1998. 28:446–457.
17. Wengerter KR, Veith FJ, Gupta SK, Ascer E, Rivers SP. Influence of vein size (diameter) on infrapopliteal reversed vein graft patency. J Vasc Surg. 1990. 11:525–531.
18. Schanzer A, Hevelone N, Owens CD, Belkin M, Bandyk DF, Clowes AW, et al. Technical factors affecting autogenous vein graft failure: observations from a large multicenter trial. J Vasc Surg. 2007. 46:1180–1190.
19. Wallace P, Ritchie JR, Richard H. Femoropopliteal occulusive disease. General Surg. 1995. 35:655–656.
20. Eskelinen E, Luther M, Eskelinen A, Lepantalo M. Infrapopliteal bypass reduces amputation incidence in elderly patients: a population-based study. Eur J Vasc Endovasc Surg. 2003. 26:65–68.
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