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Cho and Kim: Clinicopathologic Evaluation of Patients with Recurrence of Gastric Cancer within 6 Months after Curative Resection
Original Article
Journal of the Korean Surgical Society

Journal of the Korean Surgical Society 2009; 77(6): 385-390.

Published online: 4 December 2009

DOI: https://doi.org/10.4174/jkss.2009.77.6.385

Clinicopathologic Evaluation of Patients with Recurrence of Gastric Cancer within 6 Months after Curative Resection

Jeong Nam Cho, M.D., Yong Ho Kim, M.D.

Department of Surgery, Kyung Hee University College of Medicine, Seoul, Korea.

Corresponding author (khjho@khmc.or.kr)

Received 23 July 2009       Accepted 23 September 2009

Copyright © 2009 The Korean Surgical Society

Abstract

Purpose

Evaluation of the clinicopathologic characteristics of recurred gastric cancer after curative resection is useful for detection of the recurrence and care thereof. The aim of this study was evaluating the characteristics of recurrence that occur less than 6 months after curative resection for gastric cancer.

Methods

The study included 199 patients who recurred after curative gastrectomy that was performed in Kyung-Hee University Medical Center, from January 2000 to January 2008. Clinicopathologic findings were compared between 18 patients who recurred within 6 months after gastrectomy (early recurrence group) and 56 patients who recurred 2 years later (late recurrence group).

Results

When compared with the late recurrence group, the early recurrence group was characterized by extended lymph node metastasis (P=0.005), advanced stage of disease (P=0.022), shorter survival period after recurrence (P=0.001), and more hepatic metastasis (P=0.008).

Conclusion

Patients with more advanced stages of disease or those with extended lymph node metastasis have a risk of early recurrence after curative gastrectomy. Clinicopathologic characteristics related to recurrence time of gastric cancer are important in detection and effective care of recurred gastric cancer.

Keywords: Early recurrence, Curative resection, Gastric cancer

Figures and Tables

Fig. 1
Survival times after recurrence (Kaplan-Meier). There are significant differences in survival times after recurrence between patients with early and late recurrence group (P=0.001).
jkss-77-385-g001
Fig. 2
Recurrence sites and Survival curve (Kaplan-Meier). There was no statistical difference in survival times among recurrence sites (P=0.502).
jkss-77-385-g002
Table 1
Characteristics of patients who recurred after curative gastrectomy for gastric cancer
jkss-77-385-i001

*DG = distal gastrectomy; †TG = total gastrectomy; ‡LN = lymph node; §CEA = carcinoembryonic antigen.

Table 2
Management after recurrence
jkss-77-385-i002
Table 3
Comparison of the site of recurrence between early and late recurrence
jkss-77-385-i003

*C = conservative management; †P = peritoneum; ‡LN = lymph node; §CH = chemotherapy.

Table 4
Patients recurred within 6 months after gastrectomy
jkss-77-385-i004

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