Journal List > J Korean Ophthalmol Soc > v.59(3) > 1010861

Choi, Seo, Ko, Song, and Yoon: Comparison of Calcium Alginate and Polyurethane Foam Used as Nasal Packings after Endonasal Dacryocystorhinostomy

Abstract

Purpose

To compare the effectiveness of calcium alginate (Algi-pack®)and polyurethane foam (Nasopore®), two types of absorbable packing used for nasal packing after endonasal dacryocystorhinostomy.

Methods

We performed a retrospective chart review of 128 eyes of patients who underwent endonasal dacryocystorhinostomy from January 2008 to July 2016. Algi-pack® was used to pack 42 eyes and Nasopore® in 86 eyes. We compared the two groups in terms of pain on postoperative day 2; the re-bleeding frequency within 1 week; anatomical and functional success rates 3 months after surgery; and the frequencies of postoperative complications including synechiae, granulomas, and membrane formation at 3 months postoperatively.

Results

There was no significant difference between the Algi-pack® and Nasopore® groups in terms of postoperative pain or re-bleeding rate (pain: 73.8% vs. 83.7%, p = 0.38; re-bleeding: 4.8% vs. 5.8%, p = 0.058). There was no significant between-group difference in terms of the formation of synechiae, granulomas, or membranes to 3 months postoperatively (granulomas: 33.3% vs. 29.1%, p = 0.62; synechiae: 1.2% vs. 4.8%, p = 0.21; membranes: 19.0% vs. 12.8%, p = 0.35). The functional and anatomical success rates evaluated 3 months after surgery also did not differ significantly between the two groups (anatomical success: 100% vs. 97.7%, p = 0.32; functional success: 100% vs. 95.3%, p = 0.16).

Conclusions

Algi-pack® and Nasopore® equivalently suppressed bleeding after endonasal dacryocystorhinostomy and did not differentially affect the surgical success rate or the frequency of postoperative complications.

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Figure 1.
Calcium alginate (Algi-pack®). (A) Photograph of Algi-pack before insertion into the nasal cavity. (B) Clinical photographs demonstrating changes in Algi-pack® during postoperative follow-up. POD = postoperative day.
jkos-59-197f1.tif
Figure 2.
Comparison of re-bleeding that required re-packing within postoperative day 7. (A) There was no significant difference in re-bleeding within postoperative day 7 between Algi-pack® and Nasopore® groups. (B) There was no significant difference in re-bleeding between the group on antiplatelets and the group not on antiplatelets.
jkos-59-197f2.tif
Figure 3.
Comparison of visual analogue scale (VAS) results for postoperative pain on postoperative day 2. There was no significant difference in pain on postoperative day 2 between Algi-pack® and Nasopore® groups.
jkos-59-197f3.tif
Table 1.
Demographics and clinical data of subjects enrolled in this study
Algi-pack® Nasopore® p-value
No. of eyes 42 86
Age (years) 61.5 ± 10.9 59.2 ± 10.9 0.10
Gender (M/F) 8/34 (19.0/81.0) 17/69 (19.8/80.2) 0.92
Aspirin medication 5 (11.9) 13 (15.1) 0.62
DM 5 (11.9) 10 (11.6) 0.96
HTN 16 (38.1) 22 (25.6) 0.15
Canalicular stenosis 16/26 (38.1) 24/62 (27.9) 0.24

Values are presented as mean ± SD or n (%) unless otherwise indicated. Independent r-test for the comparision of age, otherwise Pearson's chi-square and Fisher exact test was used.

SD = standard deviation; M/F = male/female; DM = diabetes mellitus; HTN = hypertension.

Table 2.
Comparison of anatomical and functional success rates between Algi-pack® and Nasopore® groups
Algi-pack® Nasopore® p-value
(n = 42) (n = 86)
Anatomical success after 3 months (Assessed by fluorescein dye) 42 (100) 84 (97.7) 0.32
Functional success after 3 months (Assessed by Munk score) Postoperative nasal findings after 3 months 42 (100) 82 (95.3) 0.16
   Granulation formation 14 (33.3) 25 (29.1) 0.62
   Synechiae formation 2 (1.2) 1 (4.8) 0.21
   Membrane formation 8 (19.0) 11 (12.8) 0.35

Values are presented as number (%) unless otherwise indicated. p-values less than 0.05 were considered significantly. Pearson's chi-square and Fischer exact test were used. Postoperative nasal findings were assessed using a nasal endoscope, and any granulation, synechiae, and membrane formation within 1-2 mm of the nasal ostium were identified in postoperative 3 months.

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