Journal List > J Korean Ophthalmol Soc > v.59(2) > 1010858

J Korean Ophthalmol Soc. 2018 Feb;59(2):181-184. Korean.
Published online February 09, 2018.
©2018 The Korean Ophthalmological Society
A Case of Thelazia callipaeda Infestation with Preseptal Cellulitis
Dong Hyun Lee, MD,1 Sung Hee Park, BS,2 Hak Sun Yu, PhD,2 and Ji Eun Lee, MD, PhD1,3
1Department of Ophthalmology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.
2Department of Parasitology, Pusan National University School of Medicine, Yangsan, Korea.
3Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Pusan National University School of Medicine, Yangsan, Korea.

Address reprint requests to Ji Eun Lee, MD, PhD. Department of Ophthalmology, Pusan National University Yangsan Hospital, #20 Geumo-ro, Mulgeum-eup, Yangsan 50612, Korea. Tel: 82-55-360-2590, Fax: 82-55-360-2161, Email:
Received November 02, 2017; Revised December 03, 2017; Accepted January 22, 2018.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.



To report a case of Thelazia callipaeda infection with preseptal cellulitis.

Case summary

A 24-year-old female presented with symptoms of conjunctival injection and ocular pain in her left eye and a parasite was found in her conjunctival sac. Using light microscopy, we identified Thelazia callipaeda and many larvae were observed in the vulva of an adult female worm. Three days later, erythematous swelling occurred in the left upper eyelid and four adult worms were found and removed with forceps. Third-generation cephalosporin and nonsteroidal anti-inflammatory drugs were administered orally; the eyelid swelling improved but the conjunctival injection remained. Later five and seven adult worms were removed every 4 weeks and the conjunctival injection improved with no parasites detected after the final extraction.


In the case of Thelazia callipaeda infection, it is necessary to identify eggs and larvae and to observe the patient for more than 1 month because of postextraction growth of the larvae. In addition, the possibility of preseptal cellulitis by Thelazia callipaeda should be considered.

Keywords: Oriental eye worm; Preseptal cellulitis; Thelazia callipaeda


Figure 1
External photography of the patient. A 24-year-old woman presents eythematous swelling at her left upper eyelid.
Click for larger image

Figure 2
Light microscopy of Thelazia callipaeda detected in the patient. Light microscopy shows many larvae on tail of Thelazia callipaeda (black arrow, A: ×10 magnification, B: ×50 magnification).
Click for larger image

Figure 3
Schematic diagram of Thelazia callipaeda. There are numerous eggs and coiled embryonic larvae in uterus.
Click for larger image


Conflicts of Interest:The authors have no conflicts to disclose.

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