Journal List > J Korean Ophthalmol Soc > v.58(6) > 1010793

Bak, Yoo, Yang, and Hwang: Quantitative Pupillometry of the Pupillary Light Reflex in Koreans

Abstract

Purpose

To determine the normal ranges of various indexes of the pupillary light reflex measured by automated pupillometry in Koreans.

Methods

We retrospectively analyzed 90 healthy adults who did not have any ocular diseases other than refractive errors. The direct pupillary light reflex was measured with an automated dynamic pupillometer (PLR-200, NeurOptics Inc., Irvine, CA, USA). A total of 7 indices were measured as follows; the maximum and minimum pupil diameters, constriction latency, constriction ratio, maximum constriction velocity, average constriction velocity and average dilation velocity.

Results

There were no significant differences in quantitative indexes of the pupillary light reflex between fellow eyes. A significant decrease in maximum pupil diameter, minimum pupil diameter, maximum constriction velocity, average constriction velocity and average dilation velocity were observed with aging. In contrast, a significant increase in constriction latency was observed with aging. There were no differences in quantitative pupil measurements according to gender (p<0.001).

Conclusions

Quantitative measurements of the pupillary light reflex by dynamic pupillometry showed no significant differences between fellow eyes. A significant decrease in pupil size, constriction velocity and dilation velocity, and an increase in pupil constriction latency were observed with aging.

Figures and Tables

Figure 1

Correlations between age and quantitative measurements of the pupillary light reflex. The maximum pupil diameter (mm) (A), minimum pupil diameter (mm) (B), average constriction velocity (mm/sec) (C), average dilation velocity (mm/sec) (D) and maximum constriction velocity (mm/sec) (E) significantly decreased with age. In contrast, a significant increase in constriction latency (sec) (F) was observed with aging (r = Pearson' correlation coefficient).

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Table 1

Quantitative measurements of the pupillary light reflex

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R = right eye; SD = standard deviation; R-L = right eye-left eye.

*Significance probability of inter-eye difference between fellow eyes.

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