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Lee, Yang, Paik, and Yang: Eyelid Mass as Initial Presentation of Breast Cancer: A Case Report
Case Report

Journal of the Korean Ophthalmological Society 2017; 58(5): 591-594.

Published online: 15 May 2017

DOI: https://doi.org/10.3341/jkos.2017.58.5.591

Eyelid Mass as Initial Presentation of Breast Cancer: A Case Report

Youlim Lee, MD, Hee jung Yang, MD, Ji-sun Paik, MD, PhD, Suk-Woo Yang, MD, PhD

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Address reprint requests to Suk-Woo Yang, MD, PhD. Department of Ophthalmology, The Catholic University of Korea Seoul St. Mary's Hospital, #222 Banpo-daero, Seocho-gu, Seoul 06591, Korea. Tel: 82-2-3779-1848, Fax: 82-2-761-6869, yswoph@hanmail.net

Received 22 December 2016       Revised 9 March 2017       Accepted 19 April 2017

©2017 The Korean Ophthalmological Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

We report a case in which eyelid mass was the initial presentation of breast cancer. The diagnosis of breast cancer was made after lid biopsy.

Case summary

A 41-year-old female patient presented with a painful mass on the left lower lid after 1 month. There was a pinkish mass in the lateral portion of the tarsal conjunctiva, and computed tomography revealed a mass with an irregular margin on the lower lid connected to the left lacrimal gland. Biopsy was performed at the tarsal conjunctiva of the left eye, and histopathologic examination was suggestive of malignant epithelial cell neoplasm, especially metastatic carcinoma in the breast. The patient was diagnosed as having invasive ductal cancer, for which she is currently receiving chemotherapy.

Conclusions

Metastases to the eyelid are very rare, accounting for less than 1% of all malignant eyelid lesions. We report a patient who presented with an eyelid mass as the initial presentation of breast cancer, which was diagnosed with metastatic breast cancer.

Keywords: Breast cancer, Eyelid mass, Metastatic cancer

Figures and Tables

Figure 1

Anterior segment photographs of the mass at initial presentation. (A) An irregular palpable mass (black arrow) is seen on the lateral side of the left lower eyelid. (B) Atypical upper and lower lid swelling is seen on left eye.

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Figure 2

Non-enhance Orbit computed tomography, showing Ill-defined, soft tissue density lesion in left lower eyelid, connected to left lacrimal gland. (A) Coronal view. (B) Axial view.

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Figure 3

Overview dissection of biopsy of eyelid mass. Epithelioid cell proliferation and positive staining of (A) GCDFP-15 and (B) GATA-3 was seen, suggestive of breast origin metastatic carcinoma (A: GDCFP-15, ×40) (B: GATA-3, ×10).

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