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Shin and Chung: Efficacy of Anterior Stromal Puncture Using 5% NaCl Eye Drops for Prolonged Time in Recurrent Corneal Erosion Syndrome
Original Article

Journal of the Korean Ophthalmological Society 2017; 58(5): 503-508.

Published online: 15 May 2017

DOI: https://doi.org/10.3341/jkos.2017.58.5.503

Efficacy of Anterior Stromal Puncture Using 5% NaCl Eye Drops for Prolonged Time in Recurrent Corneal Erosion Syndrome

Da-Young Shin, MD, So Hyang Chung, MD, PhD

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Address reprint requests to So Hyang Chung, MD, PhD. Department of Ophthalmology, The Catholic University of Korea Seoul St. Mary's Hospital, #222 Banpo-daero, Seocho-gu, Seoul 06591, Korea. Tel: 82-2-2258-6203, Fax: 82-2-599-7405, chungsh@catholic.ac.kr

Received 12 January 2017       Revised 4 April 2017       Accepted 25 April 2017

©2017 The Korean Ophthalmological Society

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study is to evaluate the efficacy of the combined treatment of anterior stromal puncture with the concurrent use of 5% NaCl eye drops for 6 months for recurrent corneal erosion syndrome.

Methods

A retrospective chart review was conducted for 21 patients (21 eyes) who underwent the combined treatment of anterior stromal puncture with 5% NaCl eye drops qid for 6 months to treat recurrent corneal erosion syndromes. The patients' age, gender, history of corneal trauma, history of ocular surgery, recurrence rate, need for additional treatments after recurrence and complication were analyzed.

Results

The mean age was 42.05 ± 13.83 years (19-68 years) with no significant difference in gender, and the mean follow up period was 8.48 ± 2.76 months (6-15 months). Among the 21 eyes 14 eyes (66.7%) had a previous history of corneal trauma, 2 eyes (9.52%) had previous refractive surgery, 1 eye (4.8%) had corneal dystrophy, 2 eyes (9.5%) had diabetic mellitus and 5 eyes (28.81%) had an unknown origin. Furthermore, 3 eyes (14.3%) developed recurrences and 2 eyes were resolved with conservative treatment while 1 eye needed additional anterior stroma puncture. There was no recurrence after retreatment with anterior stroma puncture. No significant complications such as infection or inflammation developed with the exception of corneal opacity in which one patient developed glare due to corneal opacity.

Conclusions

The combined treatment of anterior stromal puncture with 5% NaCl eye drops for a prolonged time might be effective at preventing the recurrence of refractory recurrent corneal erosion syndrome with conservative treatments.

Keywords: Anterior stromal puncture, Hyperosmotic agent, Recurrent corneal erosion

Figures and Tables

Figure 1

Age and gender distribution at the time of diagnosis of recurrent corneal erosion. There was no differences between genders.

jkos-58-503-g001
Figure 2

Number of previous recurrence in 21 eyes of 21 patients with recurrent corneal erosion.

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Figure 3

Previous therapies in 21 eyes of 21 patients with recurrent corneal erosion. All 21 eyes had conservative treatment with eye drops and 3 eyes had anterior stromal puncture at other hospitals.

jkos-58-503-g003
Figure 4

Gross image of 26-Gauge needle used in anterior stromal puncture. The surgeon can bend the disposable 26-Gauge needle using a microneedle holder.

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Table 1

Risk factors in 21 eyes of 21 patients with recurrent corneal erosion

jkos-58-503-i001

LASIK = laser assisted in situ keratomileusis.

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