Journal List > J Korean Ophthalmol Soc > v.58(1) > 1010742

Lee and Lee: Comparison of Biometric Measurements and Refractive Results among Low-coherence Reflectometry, Partial Interferometry and Applanation Ultrasonography

Abstract

Purpose

To compare the measurement results and the accuracy of the predicted refractive error after cataract surgery among 3 ocular biometry devices; OA-2000®, IOL Master® and A-scan ultrasound in posterior subscapular cataracts.

Methods

Biometry measurements including axial length, anterior chamber depth and the keratometry of 80 cataractous eyes were measured using ultrasonography, OA-2000® and IOL Master®. To calculate the intraocular lens (IOL) power, the SRK/T for-mula was used and 3 months after cataract surgery, the refractive outcome was compared to the preoperatively predicted re-fractive error.

Results

The number of eyes measured by the 3 devices (A-scan, IOL Master® and OA-2000®) was 57 (group A) and the number of eyes measured by 2 devices (A-scan and OA-2000®) was 22 (group B). When cataract grading was performed based on the Lens Opacity Classification system Ⅲ, the severity of posterior subscapular opacity was significantly different between the 2 groups ( p = 0.001). Although no difference was observed in the measured biometry values including axial length, anterior cham-ber depth and keratometry in groups A and B, the predicted refractive error was significantly different in group B; OA-2000® showed a significantly higher accuracy in predicting IOL power than A-scan.

Conclusions

In cataract patients whose posterior subscapular opacity is not severe, the accuracy for predicting refractive error after cataract surgery was not significantly different among the 3 devices included in our study (A-scan, IOL Master® and OA-2000®). However, in patients with severe posterior subscapular opacity, OA-2000®, that provides a Fourier domain light source-calculated predicted refractive error of IOL may be more accurate.

References

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Table 1.
Comparison of lens opacity between group A and B
A group (n = 57) B group (n = 23) p-value*
Cataract grade of LOCS Ⅲ
Cortical 3.4 ± 1.8 2.0 ± 1.7 0.150
Nuclear 3.1 ± 0.9 2.8 ± 0.8 0.546
Posterior subcapsular 1.1 ± 1.6 4.3 ± 1.0 0.001

Values are presented as mean ± SD. LOCS Ⅲ = Lens Opacity Classfication system Ⅲ.

* Analysis of variance (student t-test).

Table 2.
Comparison of axial length, anterior chamber depth and keratometry data measured by OA-2000®, IOL Master®, A-scan and automated keratometry
OA-2000® IOL Master® A-scan Automated keratometry p-value
Group A (n = 57)
Axial length (mm) 24.05 ± 0.61 24.01 ± 0.64 23.99 ± 0.62 - 0.823*
Keratometry (D)
K1 44.0 ± 0.6 43.9 ± 0.8 - 44.0 ± 0.7 0.995*
K2 44.3 ± 0.6 44.6 ± 0.6 - 44.4 ± 0.8 0.842*
ACD 3.6 ± 0.4 3.9 ± 0.7 3.6 ± 0.6 - 0.522*
Group B (n = 23)
Axial length (mm) 24.28 ± 1.34 - 24.19 ± 1.01 0.838
Keratometry (D)
K1 43.2 ± 0.8 - - 43.1 ± 0.9 0.874
K2 44.5 ± 0.7 - - 44.2 ± 0.8 0.677
ACD 3.4 ± 0.3 - 3.5 ± 0.3 - 0.326

Values are presented as mean ± SD. D = diopters; K = keratometry; ACD = anterior chamber depth.

* Analysis of variance (ANOVA)

Analysis of variance (paired t-test).

Table 3.
Comparison of PE at 3 month post-operation among OA-2000®, IOL Master® and A-scan
OA-2000® IOL Master® A-scan p-value
Group A (n = 57)
PE (D) 0.19 ± 0.30 -0.20 ± 0.53 0.25 ± 0.76 0.541*
Range (D) -0.60~0.72 -0.80~0.75 -1.25~1.00
Eyes within (%)
±0.25 D 46 48 40
±0.5 D 81 76 78
±1.0 D 96 95 95
±1.5 D 100 100 100
Group B (n = 23)
PE (D) 0.00 ± 0.26 - 0.50 ± 0.88 0.039
Range (D) -0.58~0.41 - -1.30~1.23
Eyes within (%)
±0.25 D 43 - 35
±0.5 D 83 - 78
±1.0 D 96 - 96
±1.5 D 100 - 100

Values are presented as mean ± SD. PE = prediction error; D = diopters.

* Analysis of variance (ANOVA) after absolute value conversion of PE (D)

Analysis of variance (paired t-test) after absolute value conversion of PE (D).

Figure 1.
Correlation of measured axial length value between OA-2000® and other devices (Pearson correlation analysis). Axial length measured by OA-2000® and IOL-Master® in Group A (A) OA-2000® and A-scan in Group A (B) OA-2000® and A-scan in Group B (C).
jkos-58-43f1.tif
Figure 2.
Correlation of measured keratometry power between OA-2000® and other devices (Pearson correlation analysis). Corneal power measured by OA-2000® and autokeratometer in Group A (A) OA-2000® and IOL-Master® in Group A (B) OA-2000® and au-tokeratometer in Group B (C) OA-2000® and IOL-Master® in Group B (D).
jkos-58-43f2.tif
Figure 3.
Bland-Altman plot of axial length between OA-2000® and A-scan. LOA = limit of agreement.
jkos-58-43f3.tif
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