A Pilot Study of Changes in Tear Film Short-term Dynamics with Infrared Imaging after Phacoemulsification

Seonjoo Kim; Yuli Park; Kyung-Sun Na; Hyun-Seung Kim

doi:10.3341/jkos.2017.58.4.395

Journal List > J Korean Ophthalmol Soc > v.58(4) > 1010737

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Kim, Park, Na, and Kim: A Pilot Study of Changes in Tear Film Short-term Dynamics with Infrared Imaging after Phacoemulsification

Original Article

J Korean Ophthalmol Soc 2017;58(4):395-400.

Published online: 8 September 2017

DOI: https://doi.org/10.3341/jkos.2017.58.4.395

A Pilot Study of Changes in Tear Film Short-term Dynamics with Infrared Imaging after Phacoemulsification

Seonjoo Kim, M.D., Yuli Park, M.D., Kyung-Sun Na, MD, PhD, Hyun-Seung Kim, MD, PhD

Department of Ophthalmology and Visual Science, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

Address reprint requests to Hyun-Seung Kim, MD, PhD Department of Ophthalmology, The Catholic University of Korea Yeouido St. Mary's Hospital, #10 63-ro, Yeongdeungpo-gu, Seoul 07345, Korea Tel: 82-2-3779-1243, Fax: 82-2-761-6869 E-mail: sara514@catholic.ac.kr

This study was presented as an e-poster at the 114th Annual Meeting of the Korean Ophthalmological Society 2015.

Received 3 November 20162 February 2017 Accepted 30 March 2017

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the short-term changes in tear film dynamics with non-invasive infrared imaging measurement before and after cataract surgery as a pilot study.

Methods

Seventeen eyes of 17 patients without preoperative dry eye were enrolled in this study. Non-invasive keratograph tear break-up time (NIK-TBUT) and non-invasive keratograph tear meniscus height (NIK-TMH) were measured before and 1 day, 1 week, and 1 month after cataract surgery using a keratograph.

Results

The mean patient age was 64.47 ± 10.28 years, and 78.95% were female. Although the mean postoperative 1 day NIK-TBUT-first value was not significantly different from the preoperative value, the mean postoperative 1 week and 1 month NIK-TBUT-first values were significantly lower than preoperative values (p < 0.05). The postoperative 1 day, 1 week, and 1 month NIK-TBUT-average and the NIK-TMH values were not different from preoperative values.

Conclusions

Our study showed that cataract surgery can lead to tear film instability. And it is important to determine the long-term outcomes of surgery and whether NIK-TBUT and NIK-TMH correlate with slit lamp examination tear break-up time (SLE-TBUT) and slit lamp examination tear meniscus height (SLE-TMH).

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Keywords: Cataract surgery, Dry eye, Keratograph, Tear film

References

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Figure 1.

Screenshot of output window of Keratograph 5M for the left eye of a patient. Left panel: a dynamic video recording captures the process of tear break up. Upper right panel: the total break-up areas during the time when the eye was open. Lower right panel: In the patient, non-invasive Keratography break-up time first (NIKBUT-first) is 4.7 seconds, non-invasive Keratograph break-up time-average (NIKBUT-average) is 8.6 seconds and automatic dry eye classification is level 1.

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Figure 2.

Measurement of tear meniscus height (TMH) using Keratograph 5M . The TMH was measured perpendicular to the lid margin at the pupil center.

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Table 1.

Demographic and clinical data of subjects enrolled in this study

	Study group
No. of patients	17
Age (years)	64.47 ± 10.28
Gender (male:female)	4:13
Initial NIKBUT-first (sec)	10.74 ± 4.20
Initial NIKBUT-average (sec)	14.11 ± 3.60
Initial NIK-TMH (mm)	0.37 ± 0.15
Values are presented as mean ± SD un	nless otherwise indicated.

NIKBUT = non-invasive Keratograph break-up time; NIK-TMH = non-invasive Keratography tear meniscus height.

Table 2.

Changes of Non-invasive Keratograph tear break-up time-first & average (NIKBUT-first & average), Non-invasive Keratograph tear meniscus height (NIK-TMH) over time in the patients

Parameter of Keratograph	Preoperative day	Postoperative day
Parameter of Keratograph	Preoperative day	1 day	1 week	1 month
NIKBUT-first (sec)	10.74 ± 4.20	10.79 ± 4.91	6.39 ± 3.77	5.87 ± 2.79
p-value^*		0.97	<0.05	<0.05
NIKBUT-average (sec)	14.11 ± 3.60	14.59 ± 4.38	11.27 ± 5.21	11.28 ± 5.52
p-value^*		0.70	0.36	0.57
NIK-TMH (mm)	0.37 ± 0.15	0.35 ± 0.20	0.31 ± 0.16	0.30 ± 0.13
p-value^*		0.58	0.16	0.09

Values are presented as mean ± standard deviation otherwise indicated.

^* p-values were calculated using paired t-test, compared with preoperative day value.

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