A Pilot Study of Changes in Tear Film Short-term Dynamics with Infrared Imaging after Phacoemulsification

Seonjoo Kim; Yuli Park; Kyung-Sun Na; Hyun-Seung Kim

doi:10.3341/jkos.2017.58.4.395

Journal List > J Korean Ophthalmol Soc > v.58(4) > 1010737

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Kim, Park, Na, and Kim: A Pilot Study of Changes in Tear Film Short-term Dynamics with Infrared Imaging after Phacoemulsification

Original Article

J Korean Ophthalmol Soc 2017;58(4):395-400.

Published online: 8 September 2017

DOI: https://doi.org/10.3341/jkos.2017.58.4.395

A Pilot Study of Changes in Tear Film Short-term Dynamics with Infrared Imaging after Phacoemulsification

Seonjoo Kim, M.D., Yuli Park, M.D., Kyung-Sun Na, MD, PhD, Hyun-Seung Kim, MD, PhD

Department of Ophthalmology and Visual Science, Yeouido St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

Address reprint requests to Hyun-Seung Kim, MD, PhD Department of Ophthalmology, The Catholic University of Korea Yeouido St. Mary's Hospital, #10 63-ro, Yeongdeungpo-gu, Seoul 07345, Korea Tel: 82-2-3779-1243, Fax: 82-2-761-6869 E-mail: sara514@catholic.ac.kr

This study was presented as an e-poster at the 114th Annual Meeting of the Korean Ophthalmological Society 2015.

Received 3 November 20162 February 2017 Accepted 30 March 2017

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the short-term changes in tear film dynamics with non-invasive infrared imaging measurement before and after cataract surgery as a pilot study.

Methods

Seventeen eyes of 17 patients without preoperative dry eye were enrolled in this study. Non-invasive keratograph tear break-up time (NIK-TBUT) and non-invasive keratograph tear meniscus height (NIK-TMH) were measured before and 1 day, 1 week, and 1 month after cataract surgery using a keratograph.

Results

The mean patient age was 64.47 ± 10.28 years, and 78.95% were female. Although the mean postoperative 1 day NIK-TBUT-first value was not significantly different from the preoperative value, the mean postoperative 1 week and 1 month NIK-TBUT-first values were significantly lower than preoperative values (p < 0.05). The postoperative 1 day, 1 week, and 1 month NIK-TBUT-average and the NIK-TMH values were not different from preoperative values.

Conclusions

Our study showed that cataract surgery can lead to tear film instability. And it is important to determine the long-term outcomes of surgery and whether NIK-TBUT and NIK-TMH correlate with slit lamp examination tear break-up time (SLE-TBUT) and slit lamp examination tear meniscus height (SLE-TMH).

Keywords: Cataract surgery, Dry eye, Keratograph, Tear film

References

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Figure 1.

Screenshot of output window of Keratograph 5M for the left eye of a patient. Left panel: a dynamic video recording captures the process of tear break up. Upper right panel: the total break-up areas during the time when the eye was open. Lower right panel: In the patient, non-invasive Keratography break-up time first (NIKBUT-first) is 4.7 seconds, non-invasive Keratograph break-up time-average (NIKBUT-average) is 8.6 seconds and automatic dry eye classification is level 1.

Figure 2.

Measurement of tear meniscus height (TMH) using Keratograph 5M . The TMH was measured perpendicular to the lid margin at the pupil center.

Table 1.

Demographic and clinical data of subjects enrolled in this study

	Study group
No. of patients	17
Age (years)	64.47 ± 10.28
Gender (male:female)	4:13
Initial NIKBUT-first (sec)	10.74 ± 4.20
Initial NIKBUT-average (sec)	14.11 ± 3.60
Initial NIK-TMH (mm)	0.37 ± 0.15
Values are presented as mean ± SD un	nless otherwise indicated.

NIKBUT = non-invasive Keratograph break-up time; NIK-TMH = non-invasive Keratography tear meniscus height.

Table 2.

Changes of Non-invasive Keratograph tear break-up time-first & average (NIKBUT-first & average), Non-invasive Keratograph tear meniscus height (NIK-TMH) over time in the patients

Parameter of Keratograph	Preoperative day	Postoperative day
Parameter of Keratograph	Preoperative day	1 day	1 week	1 month
NIKBUT-first (sec)	10.74 ± 4.20	10.79 ± 4.91	6.39 ± 3.77	5.87 ± 2.79
p-value^*		0.97	<0.05	<0.05
NIKBUT-average (sec)	14.11 ± 3.60	14.59 ± 4.38	11.27 ± 5.21	11.28 ± 5.52
p-value^*		0.70	0.36	0.57
NIK-TMH (mm)	0.37 ± 0.15	0.35 ± 0.20	0.31 ± 0.16	0.30 ± 0.13
p-value^*		0.58	0.16	0.09

Values are presented as mean ± standard deviation otherwise indicated.

^* p-values were calculated using paired t-test, compared with preoperative day value.

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