Accuracy of Three Intraocular Lens-power Formulas in Predicting Refractive Outcomes in Different Intraocular Lenses

Sung Il Kang; Kun Moon; Jong Hwa Jun

doi:10.3341/jkos.2016.57.12.1891

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Kang, Moon, and Jun: Accuracy of Three Intraocular Lens-power Formulas in Predicting Refractive Outcomes in Different Intraocular Lenses

Original Article

J Korean Ophthalmol Soc 2016;57(12):1891-1896.

Published online: 25 September 2016

DOI: https://doi.org/10.3341/jkos.2016.57.12.1891

Accuracy of Three Intraocular Lens-power Formulas in Predicting Refractive Outcomes in Different Intraocular Lenses

Sung Il Kang, MD¹, Kun Moon, MD², Jong Hwa Jun, MD, PhD¹

¹Department of Ophthalmology, Keimyung University School of Medicine, Daegu, Korea

²Gang-Nam the Bright Eye Clinic, Seoul, Korea

Address reprint requests to Jong Hwa Jun, MD, PhD Department of Ophthalmology, Keimyung University Dongsan Medical Center, #56 Dalseong-ro, Jung-gu, Daegu 41931, Korea Tel: 82-53-250-7702, Fax: 82-53-250-7705 E-mail: junjonghwa@gmail.com

Received 21 July 2016 Revised 16 September 2016 Accepted 21 November 2016

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To compare the accuracy of different power-calculation formulas in predicting the postoperative refraction of three-piece and one-piece intraocular lenses (IOL).

Methods

We retrospectively reviewed the medical records of 74 eyes (62 patients) that had undergone cataract surgery involving implantation of one of two IOLs― the SENSAR^® AAB00 1-Piece Acrylic IOL (44 eyes), or the Hoya^® VA60BB 3-Piece Acrylic IOL (30 eyes)― between October 2014 and March 2015. Axial length was measured using an optical low-coherence refrac-tometry (Lenstar^®), and biometry was then calculated by the pre-installed Lenstar program, which used the SRK/II, Sanders-Retzlaff-Kraff/Theoretical (SRK/T), and Hoffer Q formulas. Mean absolute error (MAE) and mean numeric error (MNE) were measured 1 day, 1 week, 1 month, and 2 months after surgery.

Results

Using the SRK/T and Hoffer Q formulas, the one-piece IOL group differed significantly from the three-piece IOL group in terms of the MNE obtained 1 month and 2 months after surgery. Across all formulas and time points, there were no significant differences between the groups in terms of MAE.

Conclusions

There was no significant difference between the different power-calculation formulas. Starting 1 month after surgery, the three-piece IOL group showed myopic postoperative refraction compared to the predictive spherical equivalent using the SRK/T and Hoffer Q formulas.

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Keywords: Intraocular lenses, Intraocular lens power formula, Mean absolute error, Mean numeric error

References

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Table 1.

Preoperative demographic characteristics

	Group 1	Group 2	p-value
Number of patients (eyes)	38 (44)	24 (30)
Age (years)	68.66 ± 5.06	67.03 ± 6.90	0.275^*
Sex (male:female)	12:32	12:18	0.314^†
Axial length (mm)	23.31 ± 0.72	23.25 ± 0.70	0.730^*
Anterior chamber depth (mm)	3.04 ± 0.30	3.04 ± 0.39	0.974^*
Preop mean K (D)	44.17 ± 1.23	44.53 ± 1.67	0.309^*

Values are presented as mean ± standard deviations. Group 1: one piece lens type, Group 2: three piece lens type.

^* Statistical significance were tested by Independent t-test

^† Statistical significance were tested by Chi-square test.

Table 2.

Information of two intraocular lens subtypes and number of uses

	VA60BB	AAB00
Optic type	Spheric	Spheric
A constant	118.4	118.7
Piece(s)	1	3
Optic size (mm)	6	6
Overall length (mm)	12.5	13
Haptic angulation	5	0
Material (optic/haptic)	Hydrophobic Acrylic/ Hydrophobic Acrylic	Hydrophobic Acrylic/PMMA
Eyes (numbers)	30	44

PMMA = Polymethyl methacrylate.

Table 3.

Comparison mean numeric errors between intraocular lens types according to intraocular lens power formulas (SRK/II, SRK/T, Hoffer Q)

	Group 1 (n = 44)	Group 2 (n = 30)	p-value^*
Postop 1 day (diopter)
SRK/II (A)	0.34 ± 0.73	0.21 ± 0.66	0.397
SRK/T (B)	0.50 ± 0.66	0.27 ± 0.57	0.109
Hoffer Q (C)	0.56 ± 0.62	0.34 ± 0.60	0.137
p-value^†	0.307	0.688
Postop 1 week (diopter)
SRK/II (A)	–0.10 ± 0.47	0.11 ± 0.59	0.117
SRK/T (B)	0.05 ± 0.46	0.17 ± 0.59	0.387
Hoffer Q (C)	0.11 ± 0.49	0.24 ± 0.69	0.386
p-value^†	0.096	0.699
Postop 1 month (diopter)
SRK/II (A)	0.05 ± 0.49	–0.17 ± 0.45	0.050^‡
SRK/T (B)	0.20 ± 0.46	–0.11 ± 0.39	0.003^‡
Hoffer Q (C)	0.27 ± 0.46	0.03 ± 0.49	0.011^‡
p-value^†	0.093	0.496
Postop 2 months (diopter)
SRK/II (A)	–0.04 ± 0.44	–0.22 ± 0.53	0.131
SRK/T (B)	0.12 ± 0.48	–0.16 ± 0.44	0.013^‡
Hoffer Q (C)	0.18 ± 0.51	–0.08 ± 0.54	0.042^‡
p-value^†	0.099	0.577

Values are presented as mean ± standard deviations unless otherwise indicated. Group 1: one piece lens type, Group 2: three piece lens type. Postop = post operation.

^* Statistical significance were tested by Independent t-test

^† Statistical significance were tested by Analysis of variance (ANOVA) test

^‡ p < 0.05.

Table 4.

Comparison mean absolute errors between intraocular lens types according to intraocular lens power formulas (SRK/II, SRK/T, Hoffer Q)

	Group 1 (n = 44)	Group 2 (n = 30)	p-value^*
Postop 1 day (diopter)
SRK/II (A)	0.60 ± 0.54	0.49 ± 0.48	0.357
SRK/T (B)	0.63 ± 0.53	0.40 ± 0.48	0.060
Hoffer Q (C)	0.66 ± 0.51	0.49 ± 0.49	0.146
p-value^†	0.869	0.698
Postop 1 week (diopter)
SRK/II (A)	0.35 ± 0.33	0.46 ± 0.37	0.182
SRK/T (B)	0.34 ± 0.32	0.34 ± 0.21	0.123
Hoffer Q (C)	0.37 ± 0.34	0.37 ± 0.32	0.120
p-value^†	0.934	0.798
Postop 1 month (diopter)
SRK/II (A)	0.36 ± 0.33	0.37 ± 0.30	0.977
SRK/T (B)	0.39 ± 0.32	0.34 ± 0.21	0.429
Hoffer Q (C)	0.42 ± 0.32	0.37 ± 0.32	0.535
p-value^†	0.723	0.890
Postop 2 months (diopter)
SRK/II (A)	0.35 ± 0.25	0.46 ± 0.34	0.178
SRK/T (B)	0.38 ± 0.32	0.37 ± 0.27	0.928
Hoffer Q (C)	0.42 ± 0.34	0.44 ± 0.30	0.802
p-value^†	0.617	0.502

Values are presented as mean ± standard deviations unless otherwise indicated. Group 1: one piece lens type, Group 2: three piece lens type. Postop = post operation.

^* Statistical significance were tested by Independent t-test

^† Statistical significance were tested by Analysis of variance (ANOVA) test.

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