Comparison of Partial Interferometry and Ultrasound A-scan for Axial Length Measurement in Retinal Vein Occlusions

Jae Yun Sung; Dong Won Heo; Young Joon Jo; Jung Yeul Kim

doi:10.3341/jkos.2016.57.8.1228

Journal List > J Korean Ophthalmol Soc > v.57(8) > 1010362

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Sung, Heo, Jo, and Kim: Comparison of Partial Interferometry and Ultrasound A-scan for Axial Length Measurement in Retinal Vein Occlusions

Original Article

J Korean Ophthalmol Soc 2016;57(8):1228-1232.

Published online: 25 September 2016

DOI: https://doi.org/10.3341/jkos.2016.57.8.1228

Comparison of Partial Interferometry and Ultrasound A-scan for Axial Length Measurement in Retinal Vein Occlusions

Jae Yun Sung, MD¹, Dong Won Heo, MD¹, Young Joon Jo, MD, PhD^1,², Jung Yeul Kim, MD, PhD^1,²

¹Department of Ophthalmology, Chungnam National University School of Medicine, Daejeon, Korea

²Research Institute for Medical Sciences, Chungnam National University, Daejeon, Korea

Address reprint requests to Jung Yeul Kim, MD, PhD Department of Ophthalmology, Chungnam National University Hospital, #282 Munhwa-ro, Jung-gu, Daejeon 35015, Korea Tel: 82-42-280-8433, Fax: 82-42-255-3745 E-mail: kimjy@cnu.ac.kr

Received 28 January 2016 Revised 1 June 2016 Accepted 14 July 2016

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the significance of axial length, which is a known risk factor of retinal vein occlusion, we measured the axial lengthby using contact A-scan sonography and partial interferometry and compared the two values.

Methods

This study included 19 patients complaining of visual symptoms and who were diagnosed with unilateral retinal vein occlusion (RVO) with macular edema (ME). Affected eyes were classified as the study group, and healthy fellow eyes were classified as the control group. We measured the central macular thickness (CMT) and axial length (AL) of the affected and fellow eyes and compared them. CMT was measured by optical coherence tomography (Stratus OCT, Carl Zeiss, Jena, Germany), and AL was measured by interferometry (IOL Master^®, Carl Zeiss, Jena, Germany).

Results

In RVO patients, CMT was significantly different between affected eyes (485.7 ± 111.3 µm) and fellow eyes (197.8 ±29.7 µm; p < 0.001). Axial length measured by A-scan sonography was 23.06 ± 0.86 mm in the affected eyes and 23.28 ± 0.93 mm in the healthy eyes, which was statistically different (p < 0.001). However, using partial interferometry, the AL was 23.35 ±0.87 mm in the affected eyes and 23.38 ± 0.95 mm in the healthy eyes. No significant difference was found.

Conclusions

We confirmed that short AL, which was once thought to be a risk factor of RVO, results from the properties of the instruments used for measurement. Moreover, we verified that partial interferometry is more accurate for measurement of AL than A-scan sonography when retinal vein occlusion is associated with ME.

Keywords: Axial length, Central macular thickness, Macular edema, Retinal vein occlusion

References

1. Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and abdominal characteristics. Am J Ophthalmol. 1994; 117:429–41.

2. Risk factors for branch retinal vein occlusion. The Eye Disease Case-control Study Group. Am J Ophthalmol. 1993; 116:286–96.

3. Lahey JM, Tunç M, Kearney J, et al. Laboratory evaluation of abdominal states in patients with central retinal vein occlusion who are less than 56 years of age. Ophthalmology. 2002; 109:126–31.

4. Lahey JM, Kearney JJ, Tunc M. Hypercoagulable states and abdominal retinal vein occlusion. Curr Opin Pulm Med. 2003; 9:385–92.

5. Cahill MT, Stinnett SS, Fekrat S. Meta-analysis of plasma abdominal, serum folate, serum vitamin B(12), and thermolabile MTHFR genotype as risk factors for retinal vascular occlusive disease. Am J Ophthalmol. 2003; 136:1136–50.

6. Aritürk N, Oge Y, Erkan D, et al. Relation between retinal vein abdominals and axial length. Br J Ophthalmol. 1996; 80:633–6.

7. Timmerman EA, de Lavalette VW, van den Brom HJ. Axial length as a risk factor to branch retinal vein occlusion. Retina. 1997; 17:196–9.

8. Simons BD, Brucker AJ. Branch retinal vein occlusion. Axial length and other risk factors. Retina. 1997; 17:191–5.

9. Kumar A, Ahuja S, Tewari HK, et al. Short axial length: risk abdominals for central retinal vein occlusion. Ann Ophthalmol. 1994; 26:145–7.

10. Olsen T. The accuracy of ultrasonic determination of axial length in pseudophakic eyes. Acta Ophthalmol (Copenh). 1989; 67:141–4.

11. Binkhorst RD. The accuracy of ultrasonic measurement of the abdominal length of the eye. Ophthalmic Surg. 1981; 12:363–5.

12. Giers U, Epple C. Comparison of A-scan device accuracy. J Cataract Refract Surg. 1990; 16:235–42.

13. Vogel A, Dick HB, Krummenauer F. Reproducibility of optical biometry using partial coherence interferometry: intraobserver and interobserver reliability. J Cataract Refract Surg. 2001; 27:1961–8.

14. Tehrani M, Krummenauer F, Kumar R, Dick HB. Comparison of biometric measurements using partial coherence interferometry and applanation ultrasound. J Cataract Refract Surg. 2003; 29:747–52.

15. Brown MM, Brown GC, Menduke H. Central retinal vein abdominal and axial length. Ophthalmic Surg. 1990; 21:623–4.

16. Holzer MP, Mamusa M, Auffarth GU. Accuracy of a new partial coherence interferometry analyser for biometric measurements. Br J Ophthalmol. 2009; 93:807–10.

17. Rose LT, Moshegov CN. Comparison of the Zeiss IOLMaster and applanation A-scan ultrasound: biometry for intraocular lens calculation. Clin Experiment Ophthalmol. 2003; 31:121–4.

18. Connors R 3rd, Boseman P 3rd, Olson RJ. Accuracy and abdominal of biometry using partial coherence interferometry. J Cataract Refract Surg. 2002; 28:235–8.

19. Haigis W, Lege B, Miller N, Schneider B. Comparison of abdominal ultrasound biometry and partial coherence interferometry for intraocular lens calculation according to Haigis. Graefes Arch Clin Exp Ophthalmol. 2000; 238:765–73.

20. Kovács I, Ferencz M, Nemes J, et al. Intraocular lens power abdominal for combined cataract surgery, vitrectomy and peeling of abdominal membranes for macular oedema. Acta Ophthalmol Scand. 2007; 85:88–91.

21. Ueda T, Nawa Y, Hara Y. Relationship between the retinal abdominal of the macula and the difference in axial length. Graefes Arch Clin Exp Ophthalmol. 2006; 244:498–501.

Table 1.

Patient demographics

	Overall	BRVO	CRVO
Subjects	19	10	9
Age (years)	58.7 ± 8.3	56.2 ± 6.3^*	62.0 ± 9.6
Gender: Women (n, %)	9 (51.9)	4 (40.0)^*	5 (55.5)
Affected eye: Right (n, %)	10 (55.7)	6 (60.0)^*	4 (44.4)

Values are presented as mean ± SD unless otherwise indicated.

BRVO = branch retinal vein occlusion; CRVO = central retinal vein occlusion.

^* No significantly difference between BRVO and CRVO (p > 0.05, Mann-Whitney U-test).

Table 2.

Comparison of the parameters between RVO eyes with macular edema and fellow eyes without macular edema

	Affected eye	Fellow eye	p-value^*
Visual acuity	0.4 ± 0.3	1.1 ± 0.3	<0.001
IOP (mm Hg)	14.1 ± 2.5	16.1 ± 2.8	0.040
Refractive power
Spherical	+1.08 ± 0.92	+0.49 ± 1.41	0.146
Cylinder	–1.03 ± 0.82	–1.04 ± 0.58	0.847
Axial length (mm)
Sonography	23.06 ± 0.86	23.28 ± 0.93	<0.001
Interferometry	23.35 ± 0.87	23.38 ± 0.95	0.456
Foveal thickness	485.7 ± 111.3	197.8 ± 29.7	<0.001

Values are presented as mean ± SD (μ m) unless otherwise indicated.

RVO = retinal vein occlusion; IOP = intraocular pressure.

^* Wilcoxon signed rank test

TOOLS

Similar articles