A Case of Orbital MALT Lymphoma in a Patient with Rheumatoid Arthritis

Chan Joo Ahn; Nam Ju Kim

doi:10.7469/JKOS.2015.56.05.780

Journal List > J Korean Ophthalmol Soc > v.56(5) > 1010283

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Ahn and Kim: A Case of Orbital MALT Lymphoma in a Patient with Rheumatoid Arthritis

Original Article

J Korean Ophthalmol Soc 2015;56(5):780-783.

Published online: 7 September 2015

DOI: https://doi.org/10.7469/JKOS.2015.56.05.780

A Case of Orbital MALT Lymphoma in a Patient with Rheumatoid Arthritis

Chan Joo Ahn, MD¹, Nam Ju Kim, MD^1,²

¹Department of Ophthalmology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea

²Department of Ophthalmology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea

￭ Address reprint requests to Nam Ju Kim, MD Department of Ophthalmology, Seoul National University Bundang Hospital, #82 Gumi-ro 173beon-gil, Bundang-gu, Seongnam 463-707, Korea Tel: 82-31-787-7376, Fax: 82-31-787-4020 E-mail: resourceful@hanmail.net

Received 21 November 20145 January 2015 Accepted 1 April 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

초록

Purpose:

To report a case of orbital mucosa-associated lymphoid tissue (MALT) lymphoma that occurred in a patient with rheumatoid arthritis (RA).

Case summary:

A 70-year-old male with alleged RA presented with a 3-month history of spontaneous and painless upper and lower eyelid swelling in the right eye. On initial examination, palpable nodules were observed at the right upper and lower eyelids and orbital computed tomography (CT) revealed a contrast-enhancing nodule just inferior to the lacrimal gland, thus an incisional biopsy was performed. The pathological report showed malignant orbital lymphoma (low grade extranodal marginal zone B cell lymphoma of MALT). Since distant metastases were not detected on whole-body CT and positron emission tomography, the patient was advised to keep previous medication and regular follow-up examinations.

Conclusions:

The possibility of MALT lymphoma should be considered as a differential diagnosis in patients with eyelid swelling and autoimmune diseases such as RA.

Keywords: Autoimmune disease, Eyelid swelling, MALT lymphoma, Rheumatoid arthritis

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Figure 1.

External photography shows upper and lower eyelid swelling in the right eye.

Figure 2.

Orbital computed tomographic scans. (A, B) 0.6 cm sized homogenously enhancing mass was found just inferior to the right lacrimal gland (arrows). (C, D) 0.9 cm sized homogeneously enhancing mass was also found in the inferolateral orbit (arrows).

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