A Case of Eccrine Spiradenoma of the Eyelid

Min Ji Ha; Ju Wan Park; Tae Jung Kim; Kyeong Wook Lee

doi:10.7469/JKOS.2015.56.05.776

Journal List > J Korean Ophthalmol Soc > v.56(5) > 1010282

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Ha, Park, Kim, and Lee: A Case of Eccrine Spiradenoma of the Eyelid

Original Article

J Korean Ophthalmol Soc 2015;56(5):776-779.

Published online: 7 September 2015

DOI: https://doi.org/10.7469/JKOS.2015.56.05.776

A Case of Eccrine Spiradenoma of the Eyelid

Min Ji Ha, MD¹, Ju Wan Park, MD, PhD², Tae Jung Kim, MD, PhD³, Kyeong Wook Lee, MD¹

¹Saevit Eye Hospital, Goyang, Korea

²Department of Ophthalmology and Visual Science, The Catholic University of Korea College of Medicine, Seoul, Korea

³Department of Pathology, The Catholic University of Korea College of Medicine, Seoul, Korea

￭ Address reprint requests to Kyeong Wook Lee, MD Saevit Eye Hospital, #1065 Jungang-ro, Ilsandong-gu, Goyang 410-817, Korea Tel: 82-31-900-7700, Fax: 82-31-900-7777 E-mail: lkw740306@hanmail.net

Received 19 December 20144 February 2015 Accepted 1 April 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

초록

Purpose:

To report a case of eccrine spiradenoma that presented as an eyelid nodule.

Case summary:

A 61-year-old female presented with a mass in the right upper lid margin; the onset time was unknown. An ophthalmic examination revealed no abnormalities except the eyelid nodule. The nodule was 3 mm in size with a firm, smooth surface and light pinkish color, and was located near the lid margin. Excision and biopsy of the nodule was performed. The pathological findings of the specimen obtained showed islands of 2 types of lobular cells. Larger, paler cells were grouped around the central area, darker and smaller cells on the periphery. These findings were compatible with eccrine spiradenoma.

Conclusions:

Eccrine spiradenoma should be considered a differential diagnosis of a solitary eyelid tumor.

Keywords: Eccrine spiradenoma, Eyelid mass

References

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Figure 1.

Pinkish and solitary nodule of smooth-surface on the margin of the right upper eyelid.

Figure 2.

Sharply circumscribed and encapsulated tumor nodule arising within the dermis. The tumor is comprised of a dif-fuse densebasaloidcellular proliferation (H&E, ×40).

Figure 3.

Two distinct populations of neoplastic epithelial cells can be seen, dark and pale. Dark cells are small, basaloid cells with hyperchromatic nuclei located at the periphery, whereas pale cells, which are larger with vesicular nuclei and ample pale cytoplasm, tend to be near the centre of the clusters (H&E, ×100).

Figure 4.

(A) The tumor cells were positive for Periodic Acid-Schiff immunostaining (Immunohistochemical stain for the selected proteins, x400). (B) The tumor cells were positive for Cytokeratin AE1/AE3 immunostaining (Immunohistochemical stain for the selected proteins, ×200). AE = anti-cytokeratin antibody.

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