Journal List > J Korean Ophthalmol Soc > v.56(5) > 1010282

Ha, Park, Kim, and Lee: A Case of Eccrine Spiradenoma of the Eyelid

초록

Purpose:

To report a case of eccrine spiradenoma that presented as an eyelid nodule.

Case summary:

A 61-year-old female presented with a mass in the right upper lid margin; the onset time was unknown. An ophthalmic examination revealed no abnormalities except the eyelid nodule. The nodule was 3 mm in size with a firm, smooth surface and light pinkish color, and was located near the lid margin. Excision and biopsy of the nodule was performed. The pathological findings of the specimen obtained showed islands of 2 types of lobular cells. Larger, paler cells were grouped around the central area, darker and smaller cells on the periphery. These findings were compatible with eccrine spiradenoma.

Conclusions:

Eccrine spiradenoma should be considered a differential diagnosis of a solitary eyelid tumor.

References

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Figure 1.
Pinkish and solitary nodule of smooth-surface on the margin of the right upper eyelid.
jkos-56-776f1.tif
Figure 2.
Sharply circumscribed and encapsulated tumor nodule arising within the dermis. The tumor is comprised of a dif-fuse densebasaloidcellular proliferation (H&E, ×40).
jkos-56-776f2.tif
Figure 3.
Two distinct populations of neoplastic epithelial cells can be seen, dark and pale. Dark cells are small, basaloid cells with hyperchromatic nuclei located at the periphery, whereas pale cells, which are larger with vesicular nuclei and ample pale cytoplasm, tend to be near the centre of the clusters (H&E, ×100).
jkos-56-776f3.tif
Figure 4.
(A) The tumor cells were positive for Periodic Acid-Schiff immunostaining (Immunohistochemical stain for the selected proteins, x400). (B) The tumor cells were positive for Cytokeratin AE1/AE3 immunostaining (Immunohistochemical stain for the selected proteins, ×200). AE = anti-cytokeratin antibody.
jkos-56-776f4.tif
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