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초록
Purpose:
In this study we determined the correlation of axial length to lamina cribrosa thickness (LCT), prelaminar tissue thickness (PT), and anterior laminar displacement (ALD) in young healthy eyes.
Methods:
The optic discs of 60 eyes from 30 young healthy subjects with myopia were scanned using enhanced-depth imaging spectral-domain optical coherence tomography (Spectralis OCT, Heidelberg Engineering, Heidelberg, Germany). The LCT, PT, and ALD were measured at the superior midperipheral, middle, and inferior midperipheral of the optic nerve head, respectively. A linear mixed-effects model was used to determine the relationship between the axial length and the LCT, axial length and PT as well as axial length and ALD.
Results:
The mean, superior midperipheral, and middle LCT were not significantly correlated with axial length. Conversely, the inferior midperipheral LCT was negatively correlated with axial length ( p = 0.019, β = -7.34). There was no significant association between axial length and PT. Mean ALD was negatively correlated with axial length ( p = 0.022, β = -17.17).
References
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Figure 1.
En face (A-1, B-1, C-1) and B-scan images at superior midperipheral (A-2), middle (B-2), inferior midperipheral (C-2) level of optic nerve head (white line: line connecting Bruch’s membrane opening, yellow dot line: anterior and posterior margin of lamina cribrosa, yellow line: thickness of lamina cribrosa, red line: thickness of prelaminar tissue, blue line: amount of lamina cribrosa displacement).
Figure 2.
Relationships of lamina cribrosa thickness (A), prelaminar tissue thickness (B), and lamina cribrosa displacement (C) with axial length depends on locations in optic nerve head (1 = superior midperipheral, 2 = middle, 3 = inferior midperipheral, 4 = mean). p = relationship of axial length and LCT, PT and ALD by linear mixed effect model. β = regression coefficient; SE = standard error; AXL = axial length; sup = superior midperipheral; mid = middle; inf = inferior midperipheral; LCT = lamina cribrosa thickness; ALD = anterior laminar displacement; PT = prelaminar tissue thickness.
Table 1.
Baseline characteristics of study group
Table 2.
Measurements of the thickness of lamina cribrosa, prelamina tissue, and anterior laminar displacement depends at each locations in optic disc head
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