Journal List > J Korean Ophthalmol Soc > v.56(5) > 1010272

Kim and Jeong: The Comparison of PostOperative Pain between Topical Anesthesia and Monitored Anesthesia Care in Cataract Surgery

초록

Purpose:

To compare pain levels in cataract surgery under topical anesthesia only and topical anesthesia under monitored anesthesia care.

Methods:

We recruited 243 patients who were scheduled to undergo cataract surgery under topical anesthesia only or topical anesthesia with monitored anesthesia care (MAC) using fentanyl and midazolam. Anesthesia methods were selected based on the patient’s preference. All patients completed an anxiety and information scale survey preoperatively. Vital signs during the operations were recorded. A 0-to-10 visual analog scale pain score survey was conducted immediately and at 2 hours, 6 hours, and 1 day after surgery.

Results:

Of the 237 patients who completed the study, 183 patients selected topical anesthesia, and 54 patients selected MAC. Mean pain scores according to the aforementioned time points after surgery were 0.50, 0.58, 0.29, and 0.12 in the topical anesthesia group, and 0.22, 0.16, 0.06, and 0.09 in the MAC group, respectively. The differences in pain score between the two groups was statistically significant at 2 hours ( p = 0.019) and 6 hours ( p = 0.040) after surgery. The mean patient anxiety score for anesthesia was 10.50 in the topical anesthesia group and 11.41 in the MAC group ( p = 0.280). Mean systolic blood pressure at the start of surgery was 140.6 mm Hg in the topical anesthesia group, and 158.2 mmHg in the MAC group.

Conclusions:

Monitored anesthesia care consistently resulted in less pain throughout the postOperative period. However, transient systolic blood pressure should be carefully monitored for a rise related to intravenous anesthetics.

References

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Figure 1.
Subjective postOperative pain score using 0-to-10 Visual Analogue Scale (VAS) Cataract surgery using MAC consistently offered less pain throughout the postOperative period and the difference was statistically significant at postop 2 hour and 6 hour. MAC = monitored anesthesia care; op = operation. * Statistically significant ( p < 0.05).
jkos-56-715f1.tif
Table 1.
Questionnaire based on the Amsterdam Preoperative Anxiety and Information Scale (APAIS)
Item Survey title Grade
1 2 3 4 5
1 I am worried about the anesthetic.
2 The anesthetic is on my mind continually.
3 I would like to know as much as possible about the anesthesia.
4 I am worried about the procedure.
5 The procedure is on my mind continually.
6 I would like to know as much as possible about the procedure.

The measure of agreement with these statements should be graded on a five-point Likert scale from 1 = not at all to 5 = extremely. Anxiety scale consists of item 1, 2, 4, 5. Information scale consists of item 3, 6.

Table 2.
Demographics of the patients
Group Topical anesthesia only Topical anesthesia + MAC Total
N 183 54 237
Age (years) 68.4 ± 10.96 71.6 ± 7.11 69.1 ± 10.91
M:F (%) 41:59 34:66 39:61
Cataract nucleus opacity 2.80 ± 0.89 2.98 ± 0.98 2.84 ± 0.93

Values are presented as mean ± SD unless otherwise indicated.

MAC = monitored anesthesia care.

Table 3.
Patient anxiety scale
Group Anxiety for anesthesia (APAIS item 1, 2) Anxiety for procedure (APAIS item 4, 5) Anxiety score (APAIS item 1, 2, 4, 5)
Topical anesthesia only 4.97 ± 2.09/10 5.53 ± 2.27/10 10.50 ± 4.10/20
Topical anesthesia + MAC 5.50 ± 2.45/10 5.91 ± 2.58/10 11.41 ± 4.49/20
t test between group (significance) p = 0.226 p = 0.354 p = 0.280

Values are presented as mean ± SD unless otherwise indicated.

APAIS = Amsterdam preoperative anxiety and information scale; MAC = monitored anesthesia care.

Table 4.
Vital signs measured during the operation
Group Topical anesthesia only Topical anesthesia + MAC t-test between group (Significance)
When operation started      
  HR 68.49 ± 10.86 67.03 ± 11.66 p=0.080
  SBP (mm Hg) 140.63 ± 16.12 158.24 ± 21.24 p<0.001*
  DBP (mm Hg) 80.04 ± 8.97 78.30 ± 9.69 p=0.366
When operation ended      
  HR 67.55 ± 10.43 62.58 ± 10.00 p=0.011*
  SBP (mm Hg) 139.14 ± 18.17 140.21 ± 20.39 p=0.947
  DBP (mm Hg) 79.10 ± 9.74 72.00 ± 10.89 p<0.001*

MAC = monitored anesthesia care; HR = heart rate per minute; SBP = systolic blood pressure; DBP = diastolic blood pressure.

* Statistically significant ( p < 0.05).

Table 5.
Bivariate correlation analysis of postOperative pain score with various preoperative and intraoperative factors
Factors   Age Gender NO Anes. Anxiety Proc. Anxiety NPO time OP order OP time HR at start SBP at start DBP at start HR at end SBP at end DBP at end
Pain at 0 hour Pearson -0.005 -0.021 -0.059 0.086 0.099 -0.052 -0.053 0.341 0.140 -0.077 -0.045 0.096 -0.055 -0.035
Sig. 0.936 0.744 0.368 0.186 0.129 0.423 0.419 0.000* 0.031* 0.235 0.490 0.141 0.402 0.587
Pain at 2 hours Pearson -0.072 0.008 -0.076 0.119 0.153 * -0.031 -0.016 0.233* 0.109 -0.065 -0.061 0.097 -0.033 0.059
Sig. 0.269 0.899 0.246 0.067 0.018* 0.637 0.803 0.000* 0.094 0.321 0.353 0.135 0.615 0.363
Pain at 6 hours Pearson -0.130 -0.056 -0.081 -0.025 -0.028 -0.113 -0.038 0.131 0.049 0.04 -0.057 0.072 0.022 0.018
Sig 0.045* 0.392 0.214 0.697 0.669 0.082 0.563 0.044* 0.455 0.539 0.385 0.27 0.741 0.784
Pain at 1 day Pearson -0.135 0.030 0.011 0.071 0.068 -0.06 0.011 0.283 0.076 0.026 0.023 0.014 -0.027 -0.043
Sig 0.038* 0.647 0.865 0.275 0.299 0.359 0.870 0.000* 0.243 0.693 0.72 0.833 0.683 0.506

NO = cataract nucleus opacity; Anes. Anxiety = anxiety for anesthesia; Proc. Anxiety = anxiety for procedure; NPO = nothing per oral; OP = operation; HR = heart rate; SBP = systolic blood pressure; DBP = diastolic blood pressure; Sig. = significance.

* Statistically significant ( p < 0.05).

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