The Relationship between the Nuclear Density Using Scheimpflug Imaging with Phacoemulsification Parameters

Seong Gyu Min; Byung Yi Ko

doi:10.3341/jkos.2015.56.10.1552

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Min and Ko: The Relationship between the Nuclear Density Using Scheimpflug Imaging with Phacoemulsification Parameters

Original Article

J Korean Ophthalmol Soc 2015;56(10):1552-1557.

Published online: 29 August 2015

DOI: https://doi.org/10.3341/jkos.2015.56.10.1552

The Relationship between the Nuclear Density Using Scheimpflug Imaging with Phacoemulsification Parameters

Seong Gyu Min, M.D, Byung Yi Ko, M.D, PhD

partment of Ophthalmology, Konyang University College of Medicine, Daejeon, Korea

Address reprint requests to Byung Yi Ko, MD, PhD Department of Ophthalmology, Konyang University Hospital, #158 Gwanjeodong-ro, Seo-gu, Daejeon 35365, Korea Tel: 82-42-600-9258, Fax: 82-42-600-9251 E-mail: kopupil@hanmail.net

Received 9 January 201516 June 2015 Accepted 14 August 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the correlation between nuclear density measured using the Pentacam^® (Oculus Optikgerate GmbH, Wetzlar, Germany) Scheimpflug imaging system and phacoemulsification parameters.

Methods

The nuclear density was measured using maximal nuclear density with ImageJ, Pentacam^® nucleus staging (PNS), average value and maximal value in lens densitometry. Intraoperatively, effective phaco time (EPT) and balanced salt solution (BSS) used were noted and compared with the nuclear density calculation methods. As an index of corneal endothelial cells, the changes in cell density (CD) were compared with the nuclear density.

Results

Regarding EPT, maximal nuclear density with ImageJ (r = 0.379, p < 0.01) and PNS (r = 0.367, p < 0.01) were correlated positively, but the other methods were not correlated. Concerning BSS used, maximal nuclear density with ImageJ (r = 0.279, p = 0.03) and PNS (r = 0.286, p = 0.04) were positively correlated, but the other methods were not correlated. The specular micro-scopy showed that as the nuclear density increased, the postoperative CD tended to decrease, but without statistical significance.

Conclusions

Preoperative nuclear density measurements using maximal nuclear density with ImageJ or PNS were correlated with phacoemulsification parameters.

Keywords: Nuclear density, Pentacam® Scheimpflug imaging, Phacoemulsification parameters

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Figure 1.

Scheimpflug image of the lens exported to ImageJ software for measuring the maximum nuclear lens density in the region of interest, indicated by the elliptical mask.

Figure 2.

Scatter plot and relationship between maximal nu-clear density with ImageJ (pixels) and EPT (seconds). EPT = effective phaco time.

Figure 3.

Scatter plot and relationship between PNS and EPT (seconds). PNS = Pentacam® nucleus staging; EPT = effec-tive phaco time.

Figure 4.

Scatter plot and relationship between maximal nu-clear density with ImageJ (pixels) and BSS usage (mL). BSS = balanced salt solution.

Figure 5.

Scatter plot and relationship between PNS and BSS usage (mL). PNS = Pentacam® nucleus staging; BSS = balanced salt solution.

Table 1.

Distribution of LOCS III NO scores

NO scores	Number of patients
1	11
2	26
3	8
4	9
5	0
Total	54

LOCS = Lens Opacities Classification System; NO = nuclear opalescence.

Table 2.

Relationship between the lens opacity and index of specular microscopy

Lens opacity	CD
Lens opacity	r	p-value
Maximal nuclear density with ImageJ	-0.059	0.70
PNS	-0.155	0.30
Average in densitometry	-0.808	0.60
Maximum in densitometry	-0.207	0.17

CD = cell density; PNS = Pentacam® nuucleus staging.

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