Journal List > J Korean Ophthalmol Soc > v.56(9) > 1010094

Jung Ran, Kim, Sung, and Yang: A Case of Exercise-Induced Anaphylaxis Presenting with Lower Lid Angioedema

Abstract

Purpose

To describe a case of exercise-induced anaphylaxis presenting with lower lid angioedema.

Case summary

A 35-year-old female patient for the past 3 years experienced lower lid edema in her left eye after exercising. In the treadmill exercise test, sneezing, coughing, and lower lid edema in her left eye appeared 13 minutes after initiating exercise. Additionally, contrast-enhanced computed tomography scan revealed minimal soft tissue thickening of the left inferior periorbital subcutaneous area with subtle enhancement after exercise. The serum immunoglobulin E (IgE) test showed elevated total IgE levels. The patient was diagnosed with exercise-induced anaphylaxis based on the above results. We informed the patient on her trigger factors and possible symptoms and prescribed an oral antihistamine and steroid.

Conclusions

In patients presenting with facial edema or eyelid edema after exercise, the possibility of exercise-induced anaphy-laxis should be considered. In addition, we have to aware of possibility of complication such as airway obstruction or a life-threat-ening condition, and it is needed to prevent a recurrence of anaphylaxis by cooperating with other department.

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Figure 1
. Clinical photograph. (A) Clinical photograph at resting state. (B) Clinical photograph after exercise. Lowe lid edema in left eye (arrow).
jkos-56-1459f1.tif
Figure 2.
Computed tomography (CT) image. (A) Axial enhnaced CT scan reveals no significant abnormal lesion in the both lower lid area at resting state. (B) Axial enhanced CT scan reveals minimal soft tissue thickening of left inferior periorbital subcutaneous area with subtle enhancement (arrow) after exercise.
jkos-56-1459f2.tif
Table 1.
IgE MAST assay
Luminescence unit MAST class Interpretation
242 4 Very High
143-242 3 High
66-142 2 Moderate
27-65 1 Low
0-26 0 Nondetectable

IgE = immunoglobulin E; MAST = multiple allergen simulta-neous test.

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