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Abstract
Purpose:
Amyloidosis involving the eyelid is a rare condition. We report a case of primary systemic amyloidosis of the eyelid.
Case summary:
A 26-year-old female presented with multiple nodules on the bilateral upper and lower eyelids that had stopped growing several years prior. Multiple pearl-colored small nodular lesions were present on the upper and lower eyelid bilaterally and no clinically specific signs were observed. Surgical excision, biopsy and electrocauterization were performed. Histological examination showed amorphous and eosinophilic substances on hematoxylin & eosin (H&E) staining and orange-colored amy-loid deposits stained with Congo-red. Systemic evaluation showed amyloid nodules invading the vocal cords and external audi-tory canal, therefore the patient was diagnosed with primary systemic amylodosis. At the postoperative 6-month follow-up, re-currence or inflammation at the operation site was not observed.
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Figure 1.
Clinical photograph of a 26 year-old woman with multiple, yellowish nodular lesion in the right upper (A), left upper (B), right lower (C), left lower (D) eyelid.
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