Journal List > J Korean Ophthalmol Soc > v.55(6) > 1010000

Yang, Ji, and Yoon: A Case of Chronic Osteomyelitis of the Orbit

Abstract

Purpose

To report a case of chronic osteomyelitis of the orbit.

Case summary

A 61-year-old woman visited the ophthalmology clinic with a 3-month history of right periorbital swelling and pain. She had a history of ondontitis treated with oral antibiotics three months previously. A hard, tender, swollen mass was pal-pated near the right lower eyelid extending to the floor of the right orbit. Otherwise, there were no other clinically-specific ocular signs. Orbital computed tomography and bone scan findings suggested right periorbital soft tissue inflammation with underlying osteomyelitis of maxillar and zygomatic bones involving the inferior and lateral orbital walls. The patient was admitted and treat-ed with broad spectrum systemic antibiotics. After 7 days, periorbital soft tissue swelling and pain were improved, but the size of the hard mass was unchanged. Seven days after admission, incision and drainage of the periorbital hard mass near the lower eyelid and debridement of the necrotic and pyogenic tissue were performed. Histologic examination showed chronic gran-ulomatous inflammation and bony necrosis of the mass. The patient was discharged after receiving systemic antibiotics for 7 more days. At the 6-month follow-up, no recurrence or abnormal findings in the right periorbital region were observed.

Conclusions

Chronic orbital osteomyelitis should be treated with combined systemic antibiotics and surgical intervention.

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Figure 1.
(A) External photograph of the 61 year-old women with a hard tender mass in the right lower eyelid extending to the floor of the right orbit.
jkos-55-902f1.tif
Figure 2.
Orbital CT images showing bone marrow lesion with mixed osteolytic and sclerotic changes (arrows) and areas of cortical destruction with periosteal reaction (arrow heads) in right maxillary and zygomatic bones, suggesting chronic osteomyelitis (A, B). Diffuse ill-defined soft tissue infiltration in the right periorbital area (*) is also visible (C, D).
jkos-55-902f2.tif
Figure 3.
The triphasic bone scan (99mTc). (A) During blood pool phase, there is increased uptake on the right inferior orbital area. (B) During delayed phase, the uptake on the same area increased, and focal hot uptake is noted at the right upper alveolar process of the maxilla.
jkos-55-902f3.tif
Figure 4.
Histopathologic findings of (A) chronic granulomatous inflammation (H&E stain, ×200) and (B) bony necrosis (H&E stain, ×100) of the orbital mass.
jkos-55-902f4.tif
Figure 5.
Six months after the initial visit, the patient's ex-ternal appearance completely recovered.
jkos-55-902f5.tif
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