Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus : Comparison to B-Scan Ultrasonography

Eui Yong Kweon

doi:10.3341/jkos.2014.55.3.387

Journal List > J Korean Ophthalmol Soc > v.55(3) > 1009910

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Kweon: Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus : Comparison to B-Scan Ultrasonography

Original Article

J Korean Ophthalmol Soc 2014;55(3):387-390.

Published online: 7 September 2014

DOI: https://doi.org/10.3341/jkos.2014.55.3.387

Enhanced Depth Imaging Optical Coherence Tomography of Choroidal Nevus : Comparison to B-Scan Ultrasonography

Eui Yong Kweon, MD

Department of Ophthalmology, Chonbuk National University Medical School, Jeonju, Korea

Address reprint requests to Eui Yong Kweon, MD Department of Ophthalmology, Chonbuk National University Hospital, #20 Geonji-ro, Deokjin-gu, Jeonju 561-712, Korea, Tel: 82-63-250-1960, Fax: 82-63-250-1960, E-mail: key@jbnu.ac.kr

Received 17 January 201428 January 2014 Accepted 4 March 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the characteristics of choroidal nevus using the enhanced depth imaging spectral domain optical coherence tomography (EDI SD-OCT), with a comparison to the B scan ultrasound (BUS) findings.

Methods

Medical records of 124 eyes of 124 choroidal nevus patients were reviewed retrospectively. All patients underwent fundus photography (FP), EDI SD-OCT, and BUS.

Results

Of 124 eyes with choroidal nevus examined by EDI SD-OCT, 43 eyes (35%) displayed good images to study. The most common EDI-OCT imaging features included choroidal shadowing, choriocapillary thinning, retinal pigment epithelial changes, and overlying subretinal fluid. The mean nevus thickness was 817 μm (120-1850 μm) by EDI-OCT compared 1295 μm (780-2400 μm) by BUS. The mean difference in the tumor thickness between two techniques was 475 μm (27-1319 μm) (p < 0.05).

Conclusions

These results have suggested that imaging of choroidal nevus with EDI-OCT shows superior measurement of its characteristics compared with ultrasonography. The clinical utility of this modality is emerging. EDI-OCT is useful in distinguishing suspicious nevi from other chorioretinal lesions, detecting tumor re-growth along the treatment margin, and demonstrating retinal or choroid tumor location.

Keywords: Choroidal Nevus, Enhanced Depth Imaging Optical Coherent Tomography, Ultrasonography

References

1. Ng CH, Wang JJ, Mitchell P, et al. Prevalence and characteristics of choroidal nevi in an Asian vs white population. Arch Ophthalmol. 2009; 127:314–9.

2. Singh AD, Kalyani P, Topham A. Estimating the risk of malignant transformation of a choroidal nevus. Ophthalmology. 2005; 112:1784–9.

3. Shields CL, Cater J, Shields JA, et al. Combination of clinical factors predictive of growth of small choroidal melanocytic tumors. Arch Ophthalmol. 2000; 118:360–4.

4. Sakata LM, Deleon-Ortega J, Sakata V, Girkin CA. Optical coherence tomography of the retina and optic nerve - a review. Clin Experiment Ophthalmol. 2009; 37:90–9.

5. Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008; 146:496–500.

6. Kiernan DF, Mieler WF, Hariprasad SM. Spectral-domain optical coherence tomography: a comparison of modern high-resolution retinal imaging systems. Am J Ophthalmol. 2010; 149:18–31.

7. Shields CL, Materin MA, Shields JA. Review of optical coherence tomography for intraocular tumors. Curr Opin Ophthalmol. 2005; 16:141–54.

8. Shields CL, Mashayekhi A, Materin MA, et al. Optical coherence tomography of choroidal nevus in 120 patients. Retina. 2005; 25:243–52.

9. Muscat S, Parks S, Kemp E, Keating D. Secondary retinal changes associated with choroidal naevi and melanomas documented by optical coherence tomography. Br J Ophthalmol. 2004; 88:120–4.

10. Schaudig U, Hassenstein A, Bernd A, et al. Limitations of imaging choroidal tumors in vivo by optical coherence tomography. Graefes Arch Clin Exp Ophthalmol. 1998; 236:588–92.

11. Shields CL, Furuta M, Berman EL, et al. Choroidal nevus transformation into melanoma: analysis of 2514 consecutive cases. Arch Ophthalmol. 2009; 127:981–7.

12. Espinoza G, Rosenblatt B, Harbour JW. Optical coherence tomography in the evaluation of retinal changes associated with suspicious choroidal melanocytic tumors. Am J Ophthalmol. 2004; 137:90–5.

13. Materin MA, Raducu R, Bianciotto C, Shields CL. Fundus auto-fluorescence and optical coherence tomography findings in choroidal melanocytic lesions. Middle East Afr J Ophthalmol. 2010; 17:201–6.

14. Shah SU, Kaliki S, Shields CL, et al. Enhanced depth imaging optical coherence tomography of choroidal nevus in 104 cases. Ophthalmology. 2012; 119:1066–72.

15. Collaborative Ocular Melanoma Study Group. Comparison of clinical, echographic, and histopathological measurements from eyes with medium-sized choroidal melanoma in the collaborative ocular melanoma study: COMS report no. 21. Arch Ophthalmol. 2003; 121:1163–71.

Figure 1.

Color fundus photograph (FP), EDI-OCT and BUS of choroidal nevi. (A) FP showing pigmented choroidal nevus. EDI-OCT showing no drusen, RPE thinning, and thinning of choriocapillaris (CC). (B) FP showing pigmented choroidal nevus. EDI-OCT showing RPE thinning (black arrow), and normal CC. (C) FP showing pigmented choroidal nevus with overlying drusen. EDI-OCT showing drusen, trace subretinal fluid (arrowhead), RPE thinning (black arrow), and marked thinning of CC (white arrow).

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