Abstract
Purpose
To evaluate the characteristics of choroidal nevus using the enhanced depth imaging spectral domain optical coherence tomography (EDI SD-OCT), with a comparison to the B scan ultrasound (BUS) findings.
Methods
Medical records of 124 eyes of 124 choroidal nevus patients were reviewed retrospectively. All patients underwent fundus photography (FP), EDI SD-OCT, and BUS.
Results
Of 124 eyes with choroidal nevus examined by EDI SD-OCT, 43 eyes (35%) displayed good images to study. The most common EDI-OCT imaging features included choroidal shadowing, choriocapillary thinning, retinal pigment epithelial changes, and overlying subretinal fluid. The mean nevus thickness was 817 μm (120-1850 μm) by EDI-OCT compared 1295 μm (780-2400 μm) by BUS. The mean difference in the tumor thickness between two techniques was 475 μm (27-1319 μm) (p < 0.05).
Conclusions
These results have suggested that imaging of choroidal nevus with EDI-OCT shows superior measurement of its characteristics compared with ultrasonography. The clinical utility of this modality is emerging. EDI-OCT is useful in distinguishing suspicious nevi from other chorioretinal lesions, detecting tumor re-growth along the treatment margin, and demonstrating retinal or choroid tumor location.
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![]() | Figure 1.Color fundus photograph (FP), EDI-OCT and BUS of choroidal nevi. (A) FP showing pigmented choroidal nevus. EDI-OCT showing no drusen, RPE thinning, and thinning of choriocapillaris (CC). (B) FP showing pigmented choroidal nevus. EDI-OCT showing RPE thinning (black arrow), and normal CC. (C) FP showing pigmented choroidal nevus with overlying drusen. EDI-OCT showing drusen, trace subretinal fluid (arrowhead), RPE thinning (black arrow), and marked thinning of CC (white arrow). |