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Abstract
Case summary
A 15-year-old female who wore cosmetic and orthokeratology contact lenses but performed inadequate lens care visited our clinic with severe pain and visual disturbance in her left eye. On slit lamp examination, central corneal epithelial defect and stromal infiltration with radial keratoneuritis were observed. Based on clinical findings and past history, Acanthamoeba keratitis was highly suspected. The patient was treated with topical chlorhexidine 0.02% (Sigma-Aldrich Co., MO, USA) and moxifloxacin 0.5% (Vigamox®, Alcon, TX, USA) per hour with 200 mg of oral itraconazol (Sporaone®, LG, Seoul, Korea) once a day. Symptoms and corneal lesions did not improve after three days. After Serratia marsenscens was isolated from her contact lenses and solution, topical chlorhexidine 0.02% was discontinued, and intravenous ceftazidime (Tazime®, Hanmi, Seoul, Korea) and fortified ceftazidime (50 mg/mL) eye drop was added. The corneal lesion dramatically improved, and after six months of follow-up, best-corrected visual acuity was 20/20 in the affected eye.
References
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Figure 1.
Anterior segment photograph of the left eye at first visit shows corneal epithelial and stromal edema with Descemet's fold, circular corneal defect at the center, and stromal infiltration as radial keratoneuritis (black arrows).
Figure 2.
Anterior segment photograph of the left eye on day 3 reveals worsen corneal epithelial defect at center, and stromal infiltration with radial keratoneuritis (white arrows).
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