The Effect of Pathologic Myopia on the Result of Macular Hole Surgery

Sang Joon Kim; Ha Kyoung Kim

doi:10.3341/jkos.2013.54.6.887

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Kim and Kim: The Effect of Pathologic Myopia on the Result of Macular Hole Surgery

Original Article

J Korean Ophthalmol Soc 2013;54(6):887-892.

Published online: 7 September 2013

DOI: https://doi.org/10.3341/jkos.2013.54.6.887

The Effect of Pathologic Myopia on the Result of Macular Hole Surgery

Sang Joon Kim, MD, Ha Kyoung Kim, MD, PhD

Department of Ophthalmology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea

Address reprint requests to Ha Kyoung Kim, MD, PhD Department of Ophthalmology, Kangnam Sacred Heart Hospital #1 Singil-ro, Yeongdeungpo-gu, Seoul 150-950, Korea Tel: 82-2-829-5193, Fax: 82-2-848-4638, E-mail: ophkim@hallym.or.kr

Received 31 August 20125 December 2012 Accepted 22 March 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate if the presence of pathologic myopia could affect the result of macular hole surgery.

Methods

This study was a retrospective comparison of the results of macular hole surgery between a pathologic myopia group (11 eyes) and a non-pathologic myopia group (14 eyes). All patients had undergone PPV, ILM peeling and C3F8 (20%) gas temponade. BCVA, IOP and OCT findings were evaluated preoperatively and at 6 months after surgery. Postoperative BCVA, IOP and macular hole closure were compared between each groups.

Results

The only statistically significant preoperative parameter between the groups was axial length (p < 0.001). Postoperative BCVA was lower in the pathologic myopia group, but the difference was not statistically significant. The rate of macular hole closure was statistically significant higher in the non-pathologic myopia group (p < 0.001).

Conclusions

The presence of pathologic myopia may negatively affect the result of macular hole surgery. J Korean Ophthalmol Soc 2013;54(6):887-892

Keywords: Macular hole, Pathologic myopia

References

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Figure 1.

Comparison of postoperative 6-month macular hole closure between groups. Macular hole closure was observed in 11 patients after primary surgery in control group (idiopathic macular hole group). In contrast, any macular hole closure was not observed in study group (pathologic myopia group).

Table 1.

Baseline characteristic of study group (pathologic myopia group)

Number	Sex	Age	Diabetes	Preop VA (log MAR)	Postop VA (log MAR)	MH size (μ m)	Axial length (mm)	Postop IOP elevation	MH closure
1	F	70	Yes	0.8	0.7	925	31.5	Yes	No
2	F	70	No	0.7	1.2	983	26.6	No	No
3	M	45	Yes	0.4	1.2	845	32.4	Yes	No
4	F	40	No	0.7	0.8	987	29.7	No	No
5	F	66	Yes	0.3	0.3	320	31.9	No	No
6	F	60	No	0.7	0.5	345	31.6	Yes	No
7	F	61	Yes	0.5	0.7	301	32.2	No	No
8	F	72	No	0.8	0.5	979	28.3	No	No
9	F	70	Yes	0.8	0.8	952	31.5	No	No
10	F	61	Yes	1.4	1.4	837	30.7	Yes	No
11	F	61	Yes	0.5	0.7	593	30.6	No	No

VA = visual acuity; log MAR = logarithm of minimal angle of resolution; MH = macular hole; IOP = intraocular pressure.

Table 2.

Baseline characteristic of control group

Number	Sex	Age	Diabetes	Preop VA (log MAR)	Postop VA (logMAR)	MH size (μ m)	Axial length (mm)	Postop IOP elevation	MH closure
1	F	60	No	1.2	0.5	289	22.5	No	Yes
2	F	57	Yes	0.8	0.8	729	24.1	No	No
3	F	77	Yes	0.8	0.7	787	22.3	No	Yes
4	F	62	Yes	1.2	0.15	622	22.4	No	Yes
5	F	69	No	0.5	0.15	550	21.9	No	Yes
6	F	66	No	0.7	0.1	148	22.5	No	Yes
7	F	61	Yes	0.7	0.2	715	24.9	No	Yes
8	F	70	Yes	0.8	0.15	863	22.6	No	Yes
9	F	62	No	1.2	0.7	859	24.4	Yes	Yes
10	F	78	Yes	1.0	0.8	1011	21.9	No	No
11	F	63	No	0.5	0.1	504	23.0	No	Yes
12	F	85	Yes	1.0	1.2	416	24.1	No	Yes
13	F	69	No	1.4	1.4	1204	21.7	No	No
14	M	67	No	0.7	0.1	311	23.1	No	Yes

VA = visual acuity; log MAR = logarithm of minimal angle of resolution; MH = macular hole; IOP = intraocular pressure.

Table 3.

Comparison of outcomes between the study group and control group

	High myopic MH Group (Study group)	Idiopathic MH Group (Control group)	p-value
Eye	11	14
Age (years)	61.45 ± 10.41	67.57 ± 7.89	0.317
Diabetes	7/11 (63.6%)	7/14 (50%)	0.689
Macular hole size (μ m)	733.36 ± 286.89	643.43 ± 296.00	0.406
Axial length (mm)	30.64 ± 1.78	22.93 ± 1.02	<0.001^†
Preop VA (log MAR)	0.69 ± 0.29	0.89 ± 0.28	0.085
Postop VA (log MAR)	0.80 ± 0.34	0.50 ± 0.44	0.075
Preop IOP (mm Hg)	15.45 ± 1.57	14.93 ± 4.16	0.572
Postop IOP (mm Hg)	15.64 ± 2.84	14.57 ± 3.08	0.291
IOP elevation history	4/11 (36.4%)	1/14 (7.1%)	0.070
Macular hole closure (%)	0/11 (0%)	11/14 (78.6%)	<0.001^†
Retreatment success	3 (gas) → fail	3 (gas) → sucess
	2 (silicone oil) → sucess

Values are present as mean ± SD.

p < 0.05 was considered to be significant.

MH = macular hole; VA = visual acuity; log MAR = logarithm of minimal angle of resolution; IOP = intraocular pressure.

^* Macular hole.

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