Journal List > J Korean Ophthalmol Soc > v.54(1) > 1009654

Shin, Hwang, and Kim: Refractive Eerror According to the Anterior Chamber Depth and Corneal Refractive Power in Short Eyes

Abstract

Purpose

To evaluate the accuracy of the chosen formula in short eyes and the effect of the anterior chamber depth (ACD) and corneal refractive power on the accuracy.

Methods

A total of 251 eyes out of 185 patients (axial length below 22.0 mm) who underwent cataract surgery in our hospital were retrospectively studied. Introcular lens (IOL) power was calculated with the Hoffer Q, SRK II, SRK-T and Holladay 1 formulas and refractive outcome was measured. Patients were divided into 2 groups based on ACD. The accuracy of the 4 formulas was compared and the errors according to the ACD were also evaluated.

Results

In eyes with short axial lengths, all formulas showed a tendency for hyperopic shifts. The Hoffer Q formula showed significantly high predictive accuracy. This tendency for hyperopic shifts was similar in the eyes with extremely short axial length, but a large refractive error deviation was observed. The 2 groups based on ACD showed no significant difference in the refractive error, but the group with deep ACD had a tendency for hyperopic shifts. The difference of the calculated IOL power between the 4 formulas was more pronounced in eyes with lower corneal refractive power.

Conclusions

In eyes with short axial lengths, preoperative ACD and corneal refractive power had an influence on the accuracies of predicted IOL power. Therefore, these factors should be considered in IOL power determination.

References

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Figure 1.
Means and standard deviations of the absolute errors of the 4 intraocular lens calculation formulas.
jkos-54-65f1.tif
Figure 2.
Means and standard deviations of the mean errors of the 4 intraocular lens calculation formulas.
jkos-54-65f2.tif
Figure 3.
Means and standard deviations of the absolute errors of the 4 intraocular lens calculation formulas.
jkos-54-65f3.tif
Figure 4.
Means and standard deviations of the mean errors of the 4 intraocular lens calculation formulas.
jkos-54-65f4.tif
Figure 5.
Relationship between target IOL diopter and Keratometric reading.
jkos-54-65f5.tif
Table 1.
The constants used in the four formulas in three intraocular lens (IOL) subtypes
    B&L Akreos AO MI60 AMO Tecnis ZA9003 Hoya AF-1 YA-60BBR
Fomula Constant 89 eyes 64 eyes 98 eyes
SRK II A Constant 118.9 119.1 118.4
SRK-T A Constant 118.9 119.1 118.4
Holladay 1 Surgeon factor 1.44 1.61 1.84
Hoffer Q pACD Constant 5.20 5.37 5.61

ACD = anterior chamber depth.

Table 2.
Preoperative characteristics and biometry
Group All eyes Short eyes Extremely short eyes
No. (eyes) 251 212 39
Sex (M/F) 41/210 15/91 11/28
Age (yrs) 69.69 ± 14.11 69.95 ± 9.17 68.25 ± 8.71
Cataract (LOCS III) 2.2 ± 0.7 2.3 ± 0.5 2.0 ± 0.8
Axial length (mm) 21.07 ± 0.62 21.21 ± 0.34 20.29 ± 0.57
ACD (mm) 2.43 ± 0.22 2.47 ± 0.24 2.21 ± 0.19
K (D) 44.82 ± 0.56 44.60 ± 0.66 45.98 ± 0.73

Values are presented as mean ± SD.

LOCS III = Lens Opacities Classification System III; ACD = anterior chamber depth; K: corneal refractive power = keratometric diopter.

Table 3.
Mean numerical error (MNE) and Mean absolute error (MAE) according to intraocular lens power calculation formulas
Group All eyes Short eyes Extremely short eyes
MNE (D, mean ± SD)      
   SRK II –0.44 ± 0.61 –0.36 ± 0.82 –0.83 ± 0.66
   SRK-T –0.26 ± 0.56 –0.19 ± 0.25 –0.59 ± 0.33
   Holladay 1 –0.20 ± 0.75 –0.13 ± 0.53 –0.66 ± 0.49
   Hoffer Q –0.19 ± 0.47 –0.12 ± 0.33 –0.46 ± 0.20
   p-value* 0.148 0.104 0.061
MAE (D, mean ± SD)      
   SRK II 0.81 ± 0.68 0.76 ± 0.34 1.08 ± 0.60
   SRK-T 0.60 ± 0.42 0.57 ± 0.45 0.72 ± 0.59
   Holladay 1 0.61 ± 0.42 0.57 ± 0.48 0.79 ± 0.55
   Hoffer Q 0.37 ± 0.30 0.33 ± 0.21 0.56 ± 0.49
   p-value* 0.022 0.010 0.001

Values are presented as mean ± SD.

MNE = mean numeric error = the predicted postoperative diopter – actual postoperative diopter; MAE = mean absolute error = the mean absolute value of the numeric error.

* Kruskal-Wallis test.

Table 4.
Characteristics of each group according to the anterior chamber depth (ACD)
Group Group I* Group II p-value
   No. (eyes) 115 136  
   ACD (mm) 2.23 ± 0.36 2.59 ± 0.21  
   Axial length (mm) length (mm) 20.95 ± 0.70 21.16 ± 0.69 0.415
   K (D) 44.91 ± 0.19 44.74 ± 0.53 0.103
MNE (D, mean ± SD)      
   SRK/II –0.56 ± 0.48 –0.45 ± 0.23 0.139
   SRK-T –0.29 ± 0.45 –0.22 ± 0.38 0.086
   Holladay 1 –0.28 ± 0.55 –0.10 ± 0.53 0.033
   Hoffer Q –0.25 ± 0.62 –0.11 ± 0.63 0.057
   p-value 0.294 0.127  
MAE (D, mean ± SD)      
   SRK/II 0.85 ± 0.49 0.77 ± 0.61 0.154
   SRK-T 0.63 ± 0.11 0.57 ± 0.46 0.464
   Holladay 1 0.60 ± 0.19 0.61 ± 0.84 0.058
   Hoffer Q 0.40 ± 0.45 0.34 ± 0.15 0.235
   p-value 0.001 0.001  

Values are presented as mean ± SD.

MNE = mean numeric error = the predicted postoperative diopter – actual postoperative diopter; MAE = mean absolute error = the mean absolute value of the numeric error.

* Anterior chamber depth < 2.43 mm

Anterior chamber depth ≥ 2.43 mm

Paired t-test.

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