Efficacy and Intraoperative Characteristics of DisCoVisc for Cataract Surgery

A Lim Sung; Hoon Oh Tae; Seung Kim Hyun

doi:10.3341/jkos.2013.54.3.432

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Sung, Tae, and Hyun: Efficacy and Intraoperative Characteristics of DisCoVisc for Cataract Surgery

Original Article

J Korean Ophthalmol Soc 2007;54(3):432-436.

Published online: 24 August 2007

DOI: https://doi.org/10.3341/jkos.2013.54.3.432

Efficacy and Intraoperative Characteristics of DisCoVisc for Cataract Surgery

A Lim Sung, MD, Hoon Oh Tae, MD, Seung Kim Hyun, MD, PhD

Department of Ophthalmology and Visual Science, The Catholic University of Korea School of Medicine, Seoul, Korea

Address reprint requests to Hyun Seung Kim, MD, PhD Department of Ophthalmology, The Catholic University of Korea, Yeouido St. Mary's Hospital #10 63-ro, Yeongdeungpo-gu, Seoul 150-896, Korea Tel: 82-2-3779-1243, Fax: 82-2-761-6869, E-mail: sara514@catholic.ac.kr

Received 26 July 2006 Accepted 8 May 2007

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To compare the efficacy and intraoperative characteristics of DisCoVisc with those of Hyal 2000 (sodium hyaluronate 1.0%) in cataract surgery.

Methods

Cataract surgery was performed on 60 eyes in 49 patients who were diagnosed with moderate cataracts. 30 eyes were performed with DisCoVisc and a control group with 30 eyes using Hyal 2000 (sodium hyaluronate 1.0%). Phacodynamics was evaluated including ultrasound (US) time, mean US intensity, cumulative dissipated energy (CDE), and amount of used balanced salt solution. Corneal endothelium and corneal thickness were measured preoperatively and 1 day and 1 month and 2 months postoperatively.

Results

There were no statistically significant differences in phacodynamic parameters in the two groups. The central cor-neal thickness change from preoperatively to postoperatively in the DisCoVisc group was +0.07 ± 2.44 μm and Hyal 2000 group +0.84 ± 2.93 μm (p = 0.032) at 2 months. Corneal endothelial cell loss (ECL)(%) at 2 months was 7.67 ± 8.01% in DisCoVisc group and 13.23 ± 15.5% in the Hyal 2000 group (p = 0.005).

Conclusions

There was signicant difference between DisCoVisc and Hyal 2000 in the changes of CCT, ECD (Endothelial cell density). (DisCoVisc is effective and provides advantages both cohesive OVDs and dispersive OVDs).

Keywords: DisCoVisc, Endothelial cell loss, OVD (ophthalmic viscosurgical device)

References

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Figure 1.

Change of preoperative and postpoerative central corneal thickness (μm). p = 0.032.

Figure 2 .

Change of preoperative and postoperative corneal endothelial cell density (cells/mm²).

Figure 3.

Endothelial cell loss between preoperation and follow up 1 m, 2 m. ^*Endothelial cell loss rate follow up 2 m (p = 0.005).

Table 1.

Preoperative parameters

	Discovisc^Ⓡ (n = 30)	Hyal 2000^Ⓡ (n = 30)	p-value
Mean age (years)	66.82 ± 7.22	65.22 ± 8.47	0.536
Sex (male/female)	15/15	14/16	0.741
Visual acuity (log MAR)	0.54 ± 0.26	0.49 ± 0.23	0.287
Pachymetry (μm)	571.10 ± 31.47	567.90 ± 31.97	0.609
Corneal endothelial cells (cells/mm²	2762.5 ± 344.51	2691.3 ± 215.19	0.335

Values are presented as mean ± SD.

Table 2.

Intraoperative characteristics of the parameters

	Discovisc (n = 30)	Hyal 2000^Ⓡ (n = 30)	p-value
Used BSS volume (mL)	61.4 ± 16.72	57.26 ± 22.67	0.241
Average phaco power	9.67 ± 2.31	11.52 ± 3.76	0.329
Torsional time (sec)	30.16 ± 20.18	23.07 ± 17.44	0.232
Torsional amplitude	32.48 ± 20.52	39.84 ± 17.98	0.417
CDE	3.69 ± 2.98	4.26 ± 3.97	0.624
I&A time (sec.)	10.01 ± 6.9	10.08 ± 8.7	0.20

Values are presented as mean ± SD.

CDE = Cumulative Dissipataed energy = torsional amplitude × torsional time × 0.4.

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