Journal List > J Korean Ophthalmol Soc > v.54(1) > 1009588

Hong, Lee, Park, Chang, Li, and Joo: Comparison of Intraocular Pressure Correction Programs in Pentacam after Corneal Refractive Surgery

Abstract

Purpose

To evaluate the accuracy of Pentacam® built-in 5 intraocular pressure (IOP) correction programs used to measure the IOP of patients who received corneal refractive surgery.

Methods

IOP of 124 eyes from 62 patients who underwent epipolis laser in situ keratomileusis was measured with Goldmann applanation tonometry (GAT) at 6 months pre- and post-operatively. The collected data was input into Pentacam®, calculated by 5 correction programs, Ehlers, Shah, Dresden, Orssengo / Pye, Kohlhaas, and compared.

Results

The GAT-based pre- and post-operative IOP was 15.75 ± 2.24 mm Hg, and 10.72 ± 2.31 mm Hg, respectively, revealing the post-operative IOP to be significantly lower than the pre-operative IOP (p < 0.001). Among the 5 correction programs within Pentacam®, Ehlers program showed little difference between pre- and post-operative IOP values (p = 0.228) and the post-operative correction value showed no significant difference with the pre-operative GAT value (p = 0.413).

Conclusions

The Ehlers program is the most accurate among the 5 Pentacam® correction programs evaluated in the present study, and can be a useful tool for correcting the true IOP of patients which tends to be higher after corneal refractive surgery.

References

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Figure 1.
User interface imaging of Pentacam for correction of intraocular pressure.
jkos-54-26f1.tif
Figure 2.
Comparison between preoperative and postoperative IOP and IOP c. IOP was checked by Goldmann and IOP c was calculated by formula in pentacam. IOP c showed significant difference in Shah, Dresden, Orssengo / Pye, Kohlhaas formula (p = 0.015, p = 0.001, p = 0.001, p < 0.001, respectively), except in Ehlers formula (p = 0.228). IOP = intraocular pressure; IOP c = corrected intraocular pressure.
jkos-54-26f2.tif
Figure 3.
Comparison between preoperative GAT with post-operative IOP c after epi-LASIK by the 5 correction methods. There is significant difference with IOP c (by Shah, Dresden, Orssengo / Pye, Kohlhaas), but no significant difference with IOP c by Ehlers. Postoperative IOP c by Ehlers is most consistent with preoperative GAT. GAT = Goldmann applanation tonometric intraocular pressure; IOP c = corrected intraocular pressure; Epi-LASIK = epipolis laser in situ keratomileusis. * p < 0.05.
jkos-54-26f3.tif
Figure 4.
Difference between corrected preoperative IOP and corrected postoperative IOP, plotted against the mean of the two measurements. The mean difference obtained by Ehlers was 0.13 mm Hg and the 95% limit of agreement was ±0.97 mm Hg, among these 5 groups Ehlers is the smallest. Mean difference IOP = corrected preoperative IOP – corrected postoperative IOP.
jkos-54-26f4.tif
Table 1.
Subjects' demographic and clinical data
  Preoperative 6 mons Postoperative Difference*
Number (eyes) 62 (124)    
Age (yrs) 29.6 ± 2.4    
Sex (M:F) 32:30    
Mean ablation depth (μ m) 65.3 ± 12.7    
SE (D) –3.74 ± 1.59 –0.89 ± 0.52  
Goldmann-IOP (mm Hg) 15.75 ± 2.24 10.72 ± 2.31 5.37 ± 1.21
CCT (μ m) 557 ± 33 470 ± 32 72 ± 24
Corneal curvature (mm) 7.74 ± 0.24 8.51 ± 0.35 –1.56 ± 0.35

Values are presented as mean ± SD.

SE = spherical equivalent; D = diopter; CCT = central corneal thickness; IOP = intraocular pressure.

* Preoperative value – postoperative value.

Table 2.
Correlation of IOPc by 5 methods with CCT and K
Methods of correction Preoperation CCT
Preoperation K
Postoperation CCT
Postoperation K
R2 p R2 p R2 p R2 p
Ehlers 0.609 <0.001 0.179 0.282 0.649 <0.001 0.163 0.335
Shah 0.514 0.018 0.184 0.271 0.516 0.014 0.174 0.281
Dresden 0.745 <0.001 0.195 0.254 0.725 <0.001 0.198 0.253
Orssengo/Pye 0.516 0.017 0.223 0.193 0.522 0.016 0.225 0.192
Kohlhaas 0.411 0.039 0.326 0.011 0.413 0.037 0.317 0.013

K = corneal curvature; p = p-value; R2= Pearson correlation coefficient; IOP c = corrected intraocular pressure; CCT = central corneal hickness.

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