Journal List > J Korean Ophthalmol Soc > v.54(12) > 1009576

Park and Choi: A Case of Herpetic Simplex Keratitis after Application of 0.015% Tafluprost Eye Drops

Abstract

Purpose

To report a single case of herpes simplex keratitis after application of 0.015% tafluprost eye drops.

Case summary

A 68-year-old male presented with left eye discomfort, epiphora, decreased visual acuity and hyperemia. The patient was diagnosed with glaucoma 6 weeks prior and started on 0.015% tafluprost eye drops in left eye and 0.15% brimonidine in both eyes. On slit lamp examination dendritic epithelial defect was observed and the patient was diagnosed with herpes simplex keratitis. The 0.015% tafluprost treatment was discontinued and 0.15% brimonidine was applied in both eyes twice a day. The herpetic keratitis in his left eye resolved completely in 2 weeks with acyclovir ointment and oral antiviral agent. No further recurrence was observed in the following 3 months.

References

1. Wand M, Gilbert CM, Liesegang TJ. Latanoprost and herpes sim-plex keratitis. Am J Ophthalmol. 1999; 127:602–4.
crossref
2. Ekatomatis P. Herpes simplex dendritic keratitis after treatment with latanoprost for primary open angle glaucoma. Br J Ophthalmol. 2001; 85:1007–12.
crossref
3. Dios CE, Maquet DJ. Latanoprost-associated recurrent herpes sim-plex keratitis. Arch Soc Esp Oftalmol. 2000; 75:775–8.
4. Asensio Sánchez VM. Recurrent corneal keratitis associated with the use of latanoprost. Arch Soc Esp Oftalmol. 2001; 76:277.
5. Villegas VM, Diaz L, Izquierdo NJ. Herpetic keratitis in a patient who used two different prostaglandin analogue ophthalmic sol-utions: a case report. PR Health Sci J. 2008; 27:348–9.
6. Kroll DM, Schuman JS. Reactivation of herpes simplex virus kera-titis after initiating bimatoprost treatment for glaucoma. Am J Ophthalmol. 2002; 133:401–3.
crossref
7. Kothari MT, Mehta BK, Asher NS, Kothari KJ. Recurrence of bi-lateral herpes simplex virus keratitis following bimatoprost use. Indian J Ophthalmol. 2006; 54:47–8.
crossref
8. Kaye S, Choudhary A. Herpes simplex keratitisㅍ. Prog Retin Eye Res. 2006; 25:355–80.
crossref
9. Byon IS, Lee JE, Lee JS. Treatment of herpes simplex ocular dis-ease with ganciclovir ophthalmic gel. J Korean Ophthalmol Soc. 2005; 46:164–70.
10. Lee GU, Lee JH. Corticosteroid therapy in herpes simplex virus keratitis. J Korean Ophthalmol Soc. 1986; 27:493–6.
11. Dhaliwal DK, Romanowski EG, Yates KA. . Experimental laser-assisted in situ keratomileusis induces the reactivation of latent herpes simplex virus. Am J Ophthalmol. 2001; 131:506–7.
crossref
12. Krachmer JH, Mannis M, Holland E. Cornea. 2nd ed.Philadelphia: Elsevier Mosby;v. 1:2005; 1045–6.
13. Strober BE, Potash S, Grossman ME. Eyelash hypertrichosis in a patient treated with topical latanoprost. Cutis. 2001; 67:109–10.
14. Wand M. Latanoprost and hyperpigmentation of eyelashes. Arch Ophthalmol. 1997; 115:1206–8.
crossref
15. Hejkal TW, Camras CB. Prostaglandin analogs in the treatment of glaucoma. Semin Ophthalmol. 1999; 14:114–23.
crossref
16. Furuichi M, Chiba T, Abe K. . Cystoid macular edema asso-ciated with topical latanoprost in glaucomatous eyes with a normally functioning blood-ocular barrier. J Glaucoma. 2001; 10:233–6.
crossref
17. Kaufman HE, Varnell ED, Toshida H. . Effects of topical unoprostone and latanoprost on acute and recurrent herpetic keratitis in the rabbit. Am J Ophthalmol. 2001; 131:643–6.
crossref
18. Kaufman HE, Varnell ED, Thompson HW. Latanoprost increases the severity and recurrence of herpetic keratitis in the rabbit. Am J Ophthalmol. 1999; 127:531–6.
crossref
19. Kim KE, Moon JI, Chung SK, Baek NH. 3 cases of latanoprost as-sociated herpes simplex keratitis. J Korean Ophthalmol Soc. 2002; 43:1081–5.
20. Harbour DA, Blyth WA, Hill TJ. Prostaglandins enhance spread of herpes simplex virus in cell cultures. J Gen Virol. 1978; 41:87–95.
crossref
21. O'Brien WJ, Taylor JL, Ankel H, Sitenga G. Assessment of antiviral activity, efficacy, and toxicity of prostaglandin A2 in a rabbit model of herpetic keratitis. Antimicrob Agents Chemother. 1996; 40:2327–31.
22. Hill JM, Shimomura Y, Kwon BS, Gangarosa LP. Iontophoresis of epinephrine isomers to rabbit eyes induced HSV-1 ocular shedding. Invest Ophthalmol Vis Sci. 1985; 26:1299–303.
23. Nakajima T, Matsugi T, Goto W. . New fluoroprostaglandin F(2alpha) derivatives with prostanoid FP-receptor agonistic activity as potent ocular-hypotensive agents. Biol Pharm Bull. 2003; 26:1691–5.
crossref
24. Yang HS, Park HG, Choi SK. Reactivation of herpetic keratitis in a patient after using two different prostaglandin analogues. J Korean Ophthalmol. 2011; 52:1119–22.
crossref

Figure 1.
A 68-year-old male with dendritic keratitis after using 0.015% tafluprost for 1 month.
jkos-54-1950f1.tif
Figure 2.
Resolving state of dendritic keratitis after discontinuing of 0.015% tafluprost eye drop for 2 weeks.
jkos-54-1950f2.tif
TOOLS
Similar articles