A Case of Pleomorphic Adenoma Arising in the Ectopic Lacrimal Gland of the Lower Eyelid

Hyun Ho Jung; Han Jin Oh; Kyung Chul Yoon

doi:10.3341/jkos.2013.54.10.1594

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Jung, Oh, and Yoon: A Case of Pleomorphic Adenoma Arising in the Ectopic Lacrimal Gland of the Lower Eyelid

Original Article

J Korean Ophthalmol Soc 2013;54(10):1594-1598.

Published online: 3 September 2013

DOI: https://doi.org/10.3341/jkos.2013.54.10.1594

A Case of Pleomorphic Adenoma Arising in the Ectopic Lacrimal Gland of the Lower Eyelid

Hyun Ho Jung, MD, Han Jin Oh, MD, Kyung Chul Yoon, MD, PhD

Department of Ophthalmology, Chonnam National University Medical School, Gwangju, Korea

Address reprint requests to Kyung Chul Yoon, MD, PhD, Department of Ophthalmology, Chonnam National University Hospital, #42 Jebong-ro, Dong-gu, Gwangju 501-757, Korea, Tel: 82-62-220-6741, Fax: 82-62-227-1642, E-mail: kcyoon@jnu.ac.kr

Received 19 April 2013 Revised 2 May 2013 Accepted 24 August 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report a case of pleomorphic adenoma arising in the ectopic lacrimal gland of the lower eyelid.

Case summary

A 36-year-old male presented with a gradually increasing mass in the left lower eyelid that had been growing for one year. A hard, non-tender, subcutaneous mass was palpated on the lateral one-third of the left lower eyelid, and there were no clinically specific signs. Orbital computed tomography demonstrated a well-demarcated 1 × 0.7 × 0.7-cm-sized mass with heterogeneous enhancement, and complete surgical resection was performed. The mass was non-adjacent to the conjunctiva and inferior tarsal plate. Histological examination showed glandular elements embedded in a myxoid stroma. The mass was diagnosed as pleomorphic adenoma arising in the ectopic lacrimal gland. At the postoperative 6-month follow-up, there was no recurrence or abnormal finding at the operation site.

Conclusions

Pleomorphic adenoma arising in the ectopic lacrimal gland should be considered as a differential diagnosis of eyelid masses.

Keywords: Ectopic lacrimal gland, Eyelid mass, Pleomorphic adenoma

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Figure 1.

Clinical photograph of a 36-year-old man with subcutaneous mass in the left lateral lower eyelid.

Figure 2.

Orbit CT shows a 1 × 0.7 × 0.7 cm-sized, round, well defined, heterogeneously enhancing mass. Axial (A) and coronal (B) views.

Figure 3.

(A, B) A polypoid well encapsulated 1 × 0.7 × 0.5 cm-sized yellowish mass was completely excised.

Figure 4.

(A, B) Hematoxylin and eosin stained sections shows many glandular elements (arrows) embedded in myxoid ground substances (asterisks). (A) Hematoxylin and eosin stain, ×40. (B) Hematoxylin and eosin stain, ×200. (C) Tumor cells were not reacted with the antibodies against glial fibrillary acidic protein (immunostain, ×200). (D) Tumor cells were not reacted with the antibodies against S-100 protein (immunostain, ×200).

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