Journal List > J Korean Ophthalmol Soc > v.54(10) > 1009494

Park and Roh: Diagnosis and Treatment of Chronic Canaliculitis

Abstract

Purpose

To report on the clinical manifestations, species and treatments of patients with chronic canaliculitis.

Methods

From August 2003 to February 2012, 77 eyes of 77 patients who were diagnosed with chronic canaliculitis at our hospital were retrospectively analyzed.

Results

The mean period from the onset of symptoms to diagnosis was 4.7 months. The most common systemic disease associated with chronic canaliculitis was diabetes (18 eyes, 23%), and 13 eyes (17%) were related to punctual plug insertion. Main symptoms consisted of epiphora with discharge and pouting punctum. In the culture results of 55 eyes, streptococci, staphylococci, and actinomyces among other bacteria were identified. Seventy-two eyes (94%) were cured with one-snip punctoplasty with curettage.

Conclusions

Chronic canaliculitis is rare, and the clinical aspect can be obscured by chronic conjunctivitis, thus the diagnosis is often delayed. In patients who have systemic diseases such as diabetes or past history of punctual plug insertion, chronic canaliculitis should be differentiated by observing the punctum more closely. If the diagnosis is accurate at the time, chronic canaliculitis could be easily cured by a relatively simple procedure such as one-snip punctoplasty with curettage.

References

1. Kim SD, Koh SI, Kim JD. Diagnosis and therapy of canaliculitis. J Korean Ophthalmol Soc. 1998; 39:2207–10.
2. Hong JW, Lee TS. Two cases of chronic canaliculitis. J Korean Ophthalmol Soc. 1990; 31:1096–102.
3. Briscoe D, Edelstein E, Zacharopoulos I. . Actinomyces canaliculitis: diagnosis of a masquerading disease. Arch Clin Exp Ophthalmol. 2004; 242:682–6.
crossref
4. Freedman JR, Markert MS, Cohen AJ. Primary and secondary lacrimal canaliculitis: a review of literature. Surv Ophthalmol. 2011; 56:336–47.
crossref
5. Chen SX, Lee GA. SmartPlug in the management of severe dry eye syndrome. Cornea. 2007; 26:534–8.
crossref
6. Varma D, Chang B, Musaad S. A case series on chronic canaliculitis. Orbit. 2005; 24:11–4.
crossref
7. Baldursdóttir E, Sigurdsson H, Jónasson L, Gottfredsson M. Actinomycotic canaliculitis: resolution following surgery and short topical antibiotic treatment. Acta Ophthalmol. 2010; 88:367–70.
crossref
8. Vécsei VP, Huber-Spitzy V, Arocker-Mettinger E, Steinkogler FJ. Canaliculitis: Difficulties in diagnosis, differential diagnosis and comparison between conservative and surgical treatment. Ophthalmologica. 1994; 208:314–7.
crossref
9. Zaldivar RA, Bradley EA. Primary canaliculitis. Ophthal Plast Reconstr Surg. 2009; 25:481–4.
10. Lin SC, Kao SC, Tsai CC. . Clinical characteristics and factors associated the outcome of lacrimal canaliculitis. Acta Ophthalmol. 2011; 89:759–63.
crossref
11. Pavilack MA, Frueh BR. Thorough curettage in the treatment of chronic canaliculitis. Arch Ophthalmol. 1992; 110:200–2.
crossref
12. Nelson CC. Complications of Freeman plugs. Arch Ophthalmol. 1991; 109:923–4.
crossref
13. Jang JH, Chae JK, Kim BJ, Lee HB. Cases of complications after the use of punctal plugs. J Korean Ophthalmol Soc. 2005; 46:547–53.
14. Lim DK, Joo MJ, Kim JH. A case of chronic granulomatous canaliculitis induced by herrick silicone punctal plug. J Korean Ophthalmol Soc. 2005; 46:384–7.
15. Mohan ER, Kabra S, Udhay P, Madhavan HN. Intracanalicular antibiotics may obviate the need for surgical management of chronic suppurative canaliculitis. Indian J Ophthalmol. 2008; 56:338–40.
crossref
16. Ahn SM, Kim HC, Jang JW, Kim SJ. Treatment of the SmartPLUG- related canaliculitis. J Korean Ophthalmol Soc. 2009; 50:1768–73.
17. SmartPlug Study Group. Management of complications after in-sertion of the SmartPlug punctal plug: a study of 28 patients. Ophthalmology. 2006; 113:1859; e1–6.
18. Lee MJ, Choung HK, Kim NJ, Khwarg SI. One-snip punctoplasty and canalicular curettage through the punctum: a minimally invasive surgical procedure for primary canaliculitis. Ophthalmology. 2009; 116:2027–30.e2.
19. Lee MJ, Lee KW, Kim NJ. . Canaliculitis associated with SmartPLUGTM punctal plug insertion: clinical features and management. J Korean Ophthalmol Soc. 2009; 50:821–5.
20. Lee J, Flanagan JC. Complications associated with silicone intra- canalicula plugs. Ophthal Plast Reconstr Surg. 2001; 17:465–9.
21. White WL, Bartley GB, Hawes MJ. . Iatrogenic complications related to the use of Herrick lacrimal plugs. Ophthalmology. 2001; 108:1835–7.

Figure 1.
(A) Pouting punctum, Injection of the conjunctiva could be misdiagnosed as chronic recurrent conjunctivitis. (B) Mucopurulent punctual regurgitation. (C) Peripunctal erythematous swelling. (D) Pyogenic granuloma.
jkos-54-1481f1.tif
Figure 2.
SmartPLUG recovered after one-snip punctoplasty and curettage.
jkos-54-1481f2.tif
Figure 3.
(A) Freeman-type punctal plugs were eliminated from the left lower punctum. (B) This picture shows the removed Freeman-type punctal plugs. Note the two Freeman-type punctal plugs had been inserted in the same punctum.
jkos-54-1481f3.tif
Figure 4.
(A, B) Intracanalicular concretion.
jkos-54-1481f4.tif
Figure 5.
(A) Photograph showing the punctum of a patient with recurrent canaliculitis. (B) Two weeks after punctoplasty and curettage, the signs of canaliculitis had resolved completely.
jkos-54-1481f5.tif
Table 1.
Clinical characteristics, treatment, and outcome for the 77 patients studied
No. (%)
Sex
 Male 15 (19)
 Female 62 (81)
Age (years, range) 59.4 (35-91)
Mean time lapse to diagnosis (months, range) 4.7 (1-28)
Mean follow-up (month, range) 8.1 (1-68)
Systemic disease
 Diabetes mellitus 18 (23)
 Hypertension 8 (10)
 Thyroiditis 5 (6)
 Liver cirrhosis 4 (5)
 Hepatitis C 2 (3)
 Colon cancer 1 (1)
Location
 Upper canaliculus only 8 (10)
 Lower canaliculus only 67 (87)
 Both 2 (3)
Laterality
 Right 44 (57)
 Left 33 (43)
Clinical symptoms and signs
 Epiphora with discharge 70 (91)
 Pouting punctum 43 (56)
 Peripunctal erythematous swelling 36 (47)
 Punctal regurgitation 31 (40)
 Mucous discharge 21 (27)
 Conjunctival injection 18 (23)
 Medial canthal pain, swelling 6 (8)
 Pyogenic granuloma 5 (6)
 Bloody discharge 4 (5)
 Eyelid swelling 2 (3)
Treatment
 One-snip punctoplasty with curretage, syringing 77 (100)
 Presence of concretions 28 (36)
 Complication (canalicular obstruction) 3 (4)
Outcome
 Recurrent 5 (6)
 Complete remission 72 (94)
Table 2.
Clinical presentation and treatment of patients with canaliculitis after punctual plug insertion
No. Age Sex Punctal plug Area Duration of maintaining plug Microbiological profile Treatment Outcome
1 43 M SmartPLUG RLL 6.5 months One-snip punctoplasty, canalicular curettage Resolution
2 35 F SmartPLUG LLL 13 months One-snip punctoplasty, canalicular curettage Resolution
3 77 F SmartPLUG LRL 7 months One-snip punctoplasty, canalicular curettage Resolution
4 51 F SmartPLUG RLL 12 months Pseudomonasaeruginosa One-snip punctoplasty, canalicular curettage Resolution
5 66 F SmartPLUG RLL 72 months Pseudomonasaeruginosa One-snip punctoplasty, canalicular curettage Resolution
6 40 F SmartPLUG RLL 61 months One-snip punctoplasty, canalicular curettage Resolution
7 50 F SmartPLUG LLL 12 months Streptococcusgordonii One-snip punctoplasty, canalicular curettage Resolution
8 48 F SmartPLUG LLL 11 months One-snip punctoplasty, canalicular curettage Resolution
9 61 F SmartPLUG LLL 8.5 months Streptococcusspecies One-snip punctoplasty, canalicular curettage Resolution
10 63 F Freeman RLL 24 months Enterobactercloacae One-snip punctoplasty, canalicular curettage Resolution
11 55 F Freeman RLL 18 months No growth One-snip punctoplasty, canalicular curettage Resolution
12 50 F Herrick RLL 16 months One-snip punctoplasty, curettage & syringing Resolution
13 44 M Herrick LLL 39 months Staphylococcusauresus One-snip punctoplasty, curettage & syringing Resolution

M = male; F = female; RLL = right lower lid punctum; LLL = left lower lid punctum.

Table 3.
Microbiologie findings of 55 cultured lacrimal canaliculits
No. (%)
Streptococcus 16 (29)
No organism isolated 12 (22)
S. aureus 8 (14)
Actinomyces 6 (11)
Pseudomonas aeruginosa 4 (7)
E. coli 3 (5)
G (-) Delftia acidovorans 2 (4)
Neisseria species 2 (4)
Streptococcus, Actinomyces 2 (4)
Table 4.
Clinical presentation of the recurred patients
No. Age Sex Area Recurrent interval (months) Systemic disease Ocular complication Intracanalicular concretion Microbiological profile
1 53 M LLL 1 DM Blepharitis O 1. Actinomyces species
2. Staphylococcus
2 63 F RUL 3 DM Canalicular obstruction O Staphylococcus aureus
3 65 F LLL 1 Floppy eyelid syndrome X E. coli
4 46 M LLL 3 DM Blepharitis O Neisseria species
5 58 F LLL 5 X No growth

M = male; F = female; LLL = left lower lid punctum; RUL = right upper lid punctum; DM = diabetes mellitus.

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