Comparison of Laser Refractive Cataract Surgery with a Femtosecond Laser Versus Conventional Phacoemulsification

Woo Seok Lee; Sang Youp Han; Kyung Hun Lee

doi:10.3341/jkos.2013.54.8.1227

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Lee, Han, and Lee: Comparison of Laser Refractive Cataract Surgery with a Femtosecond Laser Versus Conventional Phacoemulsification

Original Article

J Korean Ophthalmol Soc 2013;54(8):1227-1235.

Published online: 7 September 2013

DOI: https://doi.org/10.3341/jkos.2013.54.8.1227

Comparison of Laser Refractive Cataract Surgery with a Femtosecond Laser Versus Conventional Phacoemulsification

Woo Seok Lee, MD, Sang Youp Han, MD, Kyung Hun Lee, MD

Sungmo Eye Hospital, Busan, Korea

Address reprint requests to Sang Youp Han, MD Sungmo Eye Hospital #409-1 Haeun-daero, Haeundae-gu, Busan 612-823, Korea Tel: 82-51-743-0775, Fax: 82-51-743-0776, E-mail: medicalhan@hanmail.net

This study was presented as a narration at the 108th Annual Meeting of the Korean Ophthalmology Society 2012.

Received 15 December 201213 March 2013 Accepted 18 May 2013

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To evaluate the surgical results and efficacy of laser refractive cataract surgery with a femtosecond laser com-pared with conventional phacoemulsification.

Methods

Thirty-one eyes from 31 patients underwent laser refractive cataract surgery (femtosecond laser group), and conventional cataract surgery with phacoemulsification was performed in 30 eyes from 30 patients (conventional group). Best corrected visual acuity, spherical equivalent, surgical induced astigmatism, corneal and ocular astigmatism, total high order aberration, Strehl ratio, objective scatter index, diameter of continuous curvilinear capsulorrhexis (CCC), distance from visual axis to the center of CCC, intraocular lens (IOL) tilt, mean absolute error, effective phaco time, average phaco power and operation time were measured to compare the 2 groups.

Results

No significant differences were found between best corrected visual acuity, spherical equivalent, surgical induced astigmatism, corneal and ocular astigmatism, total high order aberration, Strehl ratio, objective scatter index, mean abso-lute error, effective phaco time, average phaco power or operation time. Significant differences were found in the diameter of CCC, distance from visual axis to the center of CCC, and IOL tilt.

Conclusions

Results of laser refractive cataract surgery with a femtosecond laser showed more precise CCC, and more stable IOL position than conventional cataract surgery.

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Keywords: Cataract, Femtosecond laser, LenSx

References

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Figure 1.

Figure 1. Comparison (A) and distribution (B) of surgically induced astigmatism between laser refractive cataract surgery with a femtosecond laser and conventional phacoemulsification at postoperative 1 month. ^*p-value = statistical significance was calculated by Mann-Whitney test.

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Figure 2.

Preoperative and postoperative parameters (Strehl ratio (A), Objective scatter index (B)) in Optical Quality Analysis System between laser refractive cataract surgery with a femtosecond laser and conventional phacoemulsification at postoperative 1 month. ^* p-value = statistical significance was calculated by Mann-Whitney test.

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Figure 3.

Comparison (A) and dis-tribution (B) of curvilinear capsu-lorrhexis size which was meas-ured by Casia SS-1000 OCT be-tween laser refractive cataract sur-gery with a femtosecond laser and conventional phacoemulsification at postoperative 1 month (B). (A) Diameter of continuous curvilinear capsulorrhexis (mm). (B) Distribution of diameter (mm). ^*p-value = stat-istical significance was calculated by Mann-Whitney test.

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Figure 4.

The distance from visual axis to the center of continuous curvilinear capsulorrhexis (A) and Intraocular lens positioning (horizontal tilt) (B) between laser refractive cataract surgery with a femtosecond laser and conventional phacoemulsification at post-operative 1 month (B). ^* p-value = statistical significance was calculated by Mann-Whitney test.

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Figure 5.

Difference between predicted and achieved post-operative spherical equivalent refraction. Mean absolute error was analyzed 1 month after surgery. ^* p-value = statistical sig-nificance was calculated by Mann-Whitney test.

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Table 1.

Preoperative characteristics of eyes for laser refractive cataract surgery with a femtosecond laser group and conventional phacoemulsification group

Characteristic	FS laser group	Conventional group	p-value
Number of eyes (patients)	31 (31)	30 (30)	0.842
Mean age (years)	67.03 ± 12.10	68.39 ± 9.60	0.733
Gender no. (%)
Male	12 (38.7%)	15 (50.0%)	0.545
Female	19 (61.3%)	15 (50.0%)	0.611
MR spherical equivalent (D)	-0.74 ± 3.93	-1.05 ± 3.14	0.065
Axial length (mm)	24.34 ± 1.60	23.62 ± 0.96	0.449
Endothelial cell density (mm²)	2734.65 ± 333.80	2699.55 ± 364.17	0.677

Values are presented as mean ± SD.

FS = femtosecond; MR = manifest refraction; D = diopter.

Table 2.

Preoperative and postoperative visual acuity

BCVA (log MAR)	FS laser group	Conventional group	p-value
Preoperative	0.33 ± 0.3	0.43 ± 0.47	0.060
Postoperative 1 week	0.09 ± 0.15	0.08 ± 0.08	0.643
Postoperative 1 month	0.06 ± 0.12	0.07 ± 0.08	0.233
Postoperative 2 months	0.01 ± 0.02	0.08 ± 0.09	0.350

Values are presented as mean ± SD.

BCVA = best corrected visual acuity; FS = femtosecond.

Table 3.

Preoperative and postoperative ocular aberrations were measured at the 4.0 mm and 6.0 mm optical zone. Aberration pa-rameters were included ocular astigmatism, corneal astigmatism, and total high order aberration by KR-1W aberrometer

	FS laser group	Conventional group	p-value
Astigmatism (4 mm optical zone)
Preoperative
Ocular	-1.33 ± 0.74	-1.20 ± 0.74	0.432
Corneal	-1.24 ± 0.92	-1.08 ± 0.58	0.732
Postoperative 1 month
Ocular	-0.82 ± 0.53	-0.89 ± 0.64	0.453
Corneal	-1.11 ± 0.72	-0.98 ± 0.63	0.395
Astigmatism (6 mm optical zone)
Preoperative
Ocular	-1.33 ± 0.74	-1.24 ± 0.78	0.563
Corneal	-0.88 ± 0.64	-0.77 ± 0.44	0.782
Postoperative 1 month
Ocular	-0.87 ± 0.59	-0.76 ± 0.55	0.343
Corneal	-0.77 ± 0.54	-0.73 ± 0.46	0.802
Total high order aberration (4 mm optical zone)
Preoperative
Ocular	0.24 ± 0.11	0.27 ± 0.16	0.796
Corneal	0.18 ± 0.08	0.15 ± 0.05	0.164
Internal	0.20 ± 0.11	0.24 ± 0.18	0.957
Postoperative 1 month
Ocular	0.18 ± 0.09	0.20 ± 0.10	0.330
Corneal	0.19 ± 0.10	0.19 ± 0.09	0.902
Internal	0.12 ± 0.05	0.13 ± 0.06	0.914
Total high order aberration (6 mm optical zone)
Preoperative
Ocular	0.69 ± 0.34	0.86 ± 0.28	0.011
Corneal	0.50 ± 0.21	0.46 ± 0.10	0.574
Internal	0.58 ± 0.32	0.66 ± 0.41	0.563
Postoperative 1 month
Ocular	0.63 ± 0.25	0.77 ± 0.30	0.138
Corneal	0.50 ± 0.13	0.52 ± 0.18	0.865
Internal	0.43 ± 0.18	0.43 ± 0.18	0.777

Values are presented as mean ± SD.

Table 4.

Effective phaco time, average phaco power, operation time were analyzed between laser refractive cataract surgery with a femtosecond laser and conventional phacoemulsification

Parameters	Grading	FS laser	Conventional	p-value
Effective phaco time (sec)	LOCS III NO 1,2	4.52 ± 2.71	3.4 ± 1.4	0.271
	LOCS III NO 3,4	7.38 ± 2.82	8.36 ± 5.34	0.983
	LOCS III NO 5,6	14.49 ± 10.14	12.41 ± 4	0.563
Average phaco power (%)	LOCS III NO 1,2	19.29 ± 8.16	26.16 ± 2.44	0.181
	LOCS III NO 3,4	24.54 ± 5.48	25.33 ± 3.13	0.723
	LOCS III NO 5,6	32.39 ± 15.80	26.88 ± 5.11	0.266
OP time (min)	LOCS III NO 1,2	13.04 ± 2.45	13.63 ± 2.92	0.639
	LOCS III NO 3,4 LOCS III NO 5,6	14.88 ± 2.09 18.13 ± 5.25	13.57 ± 2.47 16.38 ± 5.10	0.069 0.456

Values are presented as mean ± SD. LOCS = lens opacities classification system; NO = nuclear opacity; OP time = operation time.

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