Quality of Life Assessment in Patients with Wet Age-Related Macular Degeneration

So Young Han; Jeong Hoon Bae; Su Jeong Song

doi:10.3341/jkos.2012.53.4.528

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Han, Bae, and Song: Quality of Life Assessment in Patients with Wet Age-Related Macular Degeneration

Original Article

Journal of the Korean Ophthalmological Society

Journal of the Korean Ophthalmological Society 2012; 53(4): 528-535.

Published online: 17 April 2012

DOI: https://doi.org/10.3341/jkos.2012.53.4.528

Quality of Life Assessment in Patients with Wet Age-Related Macular Degeneration

So Young Han, MD, Jeong Hoon Bae, MD, Su Jeong Song, MD

Deparment of Ophthalmology, Kangbuk Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Address reprint requests to Su Jeong Song, MD. Deparment of Ophthalmology, Kangbuk Samsung Medical Center, #29 Saemunan-ro, Jongno-gu, Seoul 110-746, Korea. Tel: 82-2-2001-2250, Fax: 82-2-2001-2262, eye-su@hanmail.net

Received 13 January 2011 Accepted 16 March 2012

Abstract

Purpose

This study was performed to assess the relationship between wet age-related macular degeneration (AMD) and quality of life (QOL).

Methods

The National Eye Institute Visual Functioning Questionnaire 25 was administered to 27 wet AMD patients under treatment at Kangbuk Samsung hospital ophthalmology clinic. The relationship between wet AMD and QOL was analyzed according to age, visual acuity status and general health status.

Results

Older patients and those with hypertension had significantly lower mean scores for general vision, near vision, distance vision, vision-specific role difficulties and dependency compared to their younger and normotensive counterparts. Patients with cataracts had lower mean scores for general vision and color vision than those without, and patients with unilateral AMD had higher mean scores on the driving subscale of the questionnaire.

Conclusions

Wet AMD has a substantial impact on patient quality of life. A comprehensive approach is required in managing these patients, including treatment of comorbidities such as cataracts and psychological reassurance.

Keywords: Quality of life, Wet age-related macular degeneration

Figures and Tables

Table 1

Patient demographics

Values are presented as n (%).

SD = standard deviation; PDT = photodynamic therapy.

Table 2

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales mean scores by sex

Data are summarized as mean ± standard deviation.

^*Adjusted for age.

Table 3

Partial correlation between age and National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales scores

^*Pearson correlation coefficient; ^†Adjusted for sex; ^‡p < 0.05; ^§p < 0.001.

Table 4

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales mean scores by diabetes and hypertension

Data are summarized as mean ± standard deviation.

^*Adjusted for age and sex; ^†4 diabetes participants did not drive because of reasons other than eyesight.

Table 5

Partial correlation between visual acuity and National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales scores

^*Pearson correlation coefficient; ^†Adjusted for age, sex; ^‡p < 0.05.

Table 6

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales mean scores by lens status

Data are summarized as mean ± standard deviation.

^*Adjusted for age, sex; ^†Adjusted for age, sex, diabetes, hypertension; ^‡Same footnotes denote significant differences of the mean values between group 1 and group 3 in post-hoc analyses, p < 0.05; ^§Same footnotes denote significant differences of the mean values between group 2 and group 3 in post-hoc analyses, p < 0.05; ^∥4 pseudophakia participants did not drive because of reasons other than eyesight.

Table 7

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales mean scores by visual acuity status in both eyes

Data are summarized as mean ± standard deviation.

^*Adjusted for age, sex; ^†Adjusted for age, sex, diabetes, hypertension.

Table 8

National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) subscales mean scores by affected eye

Data are summarized as mean ± standard deviation.

^*Adjusted for age, sex; ^†Adjusted for age, sex, diabetes, hypertension.

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