Abstract
Purpose
To investigate the effects of two different opening patterns in neodymium:yttrium-aluminum-garnet (Nd:YAG) laser posterior capsulotomy on visual function.
Methods
A randomized prospective study was conducted on 62 pseudophakic eyes from 50 patients with posterior capsular opacification (PCO). Groups A and B underwent laser posterior capsulotomy with a cruciate opening and a modified circular opening, respectively. The best corrected visual acuity (BCVA), contrast sensitivity, and glare sensitivity were measured before and after laser posterior capsulotomy in both groups. The occurrences of intraocular lens (IOL) pittings were investigated and compared between the two groups.
Results
After laser capsulotomy, there were significant increases in BCVA, contrast and glare sensitivity in both groups and no significant differences between the two groups. However, group A had significantly more patients with three or more IOL pittings within a 1.5-mm radius from the IOL center (p = 0.047). In group A, these patients had significantly less contrast sensitivity (p = 0.023 in 1.6 cpd) and glare sensitivity (p = 0.043 in 1.6 cpd) than did patients with two or fewer IOL pittings.
Figures and Tables
Table 4
SD = standard deviation; BCVA = best corrected visual acuity; CPD = cycle per degree; IOL = intraocular lens.
*Three or more IOL pittings within 1.5-mm radius from IOL center; †Two or less IOL pittings within 1.5-mm radius from IOL center.
‡Statistical significances between group A and B were tested by Paired t-test; §Statistical significances between group A and B were tested by Mann-Whitney U-test.
References
1. Dangel ME, Kirkham SM, Phipps MJ. Posterior capsule opacification in extracapsular cataract extraction and the triple procedure: a comparative study. Ophthalmic Surg. 1994. 25:82–87.
2. Apple DJ, Mamalis N, Loftfield K, et al. Complications of intraocular lenses. A historical and histopathological review. Surv Ophthalmol. 1984. 29:1–54.
3. Tan JC, Spalton DJ, Arden GB. The effect of neodymium: YAG capsulotomy on contrast sensitivity and the evaluation of methods for its assessment. Ophthalmology. 1999. 106:703–709.
4. Magno BV, Datiles MB, Lasa MS, et al. Evaluation of visual function following neodymium:YAG laser posterior capsulotomy. Ophthalmology. 1997. 104:1287–1293.
5. Weiblinger RP. Review of the clinical literature on the use of the Nd:YAG laser for posterior capsulotomy. J Cataract Refract Surg. 1986. 12:162–170.
6. Goble RR, O'Brart DP, Lohmann CP, Fitzke F, Marshall J. The role of light scatter in the degradation of visual performance before and after Nd:YAG capsulotomy. Eye (Lond). 1994. 8(Pt 5):530–534.
7. Georgopoulos M, Findl O, Menapace R, et al. Influence of intraocular lens material on regeneratory posterior capsule opacification after neodymium:YAG laser capsulotomy. J Cataract Refract Surg. 2003. 29:1560–1565.
8. Schaumberg DA, Dana MR, Christen WG, Glynn RJ. A systematic overview of the incidence of posterior capsule opacification. Ophthalmology. 1998. 105:1213–1221.
9. Sterling S, Wood TO. Effect of intraocular lens convexity on posterior capsule opacification. J Cataract Refract Surg. 1986. 12:655–657.
10. Nishi O. Incidence of posterior capsule opacification in eyes with and without posterior chamber intraocular lenses. J Cataract Refract Surg. 1986. 12:519–522.
11. Frezzotti R, Caporossi A. Pathogenesis of posterior capsular opacification. Part I. Epidemiological and clinico-statistical data. J Cataract Refract Surg. 1990. 16:347–352.
12. Moisseiev J, Bartov E, Schochat A, Blumenthal M. Long-term study of the prevalence of capsular opacification following extracapsular cataract extraction. J Cataract Refract Surg. 1989. 15:531–533.
13. Emery J. Capsular opacification after cataract surgery and capsule. Curr Opin Ophthalmol. 1998. 9:60–65.
14. Apple DJ, Solomon KD, Tetz MR, et al. Posterior capsule opacification. Surv Ophthalmol. 1992. 37:73–116.
15. Chambless WS. Neodymium:YAG laser posterior capsulotomy results and complications. J Am Intraocul Implant Soc. 1985. 11:31–32.
16. Gardner KM, Straatsma BR, Pettit TH. Neodymium: YAG laser posterior capsulotomy: the first 100 cases at UCLA. Ophthalmic Surg. 1985. 16:24–28.
17. Stark WJ, Worthen D, Holladay JT, Murray G. Neodymium: YAG lasers. An FDA report. Ophthalmology. 1985. 92:209–212.
18. Wasserman EL, Axt JC, Sheets JH. Neodymium: YAG laser posterior capsulotomy. J Am Intraocul Implant Soc. 1985. 11:245–248.
19. Sunderraj P, Villada JR, Joyce PW, Watson A. Glare testing in pseudophakes with posterior capsule opacification. Eye (Lond). 1992. 6(Pt 4):411–413.
20. Bath PE, Fankhauser F. Long-term results of Nd:YAG laser posterior capsulotomy with the Swiss laser. J Cataract Refract Surg. 1986. 12:150–153.
21. Krauss JM, Puliafito CA, Miglior S, et al. Vitreous changes after neodymium-YAG laser photodisruption. Arch Ophthalmol. 1986. 104:592–597.
22. Newland TJ, McDermott ML, Eliott D, et al. Experimental neodymium: YAG laser damage to acrylic, poly(methyl methacrylate), and silicone intraocular lens materials. J Cataract Refract Surg. 1999. 25:72–76.
23. Ranta P, Tommila P, Immonen I, et al. Retinal breaks before and after neodymium:YAG posterior capsulotomy. J Cataract Refract Surg. 2000. 26:1190–1197.
24. Sheard RM, Goodburn SF, Comer MB, et al. Posterior vitreous detachment after neodymium:YAG laser posterior capsulotomy. J Cataract Refract Surg. 2003. 29:930–934.
25. Hu CY, Woung LC, Wang MC. Change in the area of laser posterior capsulotomy: 3 month follow-up. J Cataract Refract Surg. 2001. 27:537–542.
26. Aslam TM, Dhillon B. Neodymium:YAG laser capsulotomy: a clinical morphological analysis. Graefes Arch Clin Exp Ophthalmol. 2002. 240:972–976.