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Kim: Moxifloxacin Mixed Augmented Amniotic Membrane Transplantation for Perforating Infectious Keratitis
Case Report
Journal of the Korean Ophthalmological Society

Journal of the Korean Ophthalmological Society 2012; 53(2): 342-347.

Published online: 15 February 2012

DOI: https://doi.org/10.3341/jkos.2012.53.2.342

Moxifloxacin Mixed Augmented Amniotic Membrane Transplantation for Perforating Infectious Keratitis

Hong Kyun Kim, MD, PhD

Department of Ophthalmology, Kyungpook National University School of Medicine, Daegu, Korea.

Address reprint requests to Hong Kyun Kim, MD, PhD. Department of Ophthalmology, Kyungpook National University Hospital, #130 Dongdeok-ro, Jung-gu, Daegu 700-721, Korea. Tel: 82-53-420-5806, Fax: 82-53-426-6552, okeye@knu.ac.kr

Received 22 August 2011       Accepted 26 December 2011

Copyright © 2012 The Korean Ophthalmological Society

Abstract

Purpose

To report the clinical results of moxifloxacin mixed augmented amniotic membrane transplantation (AMT) in 2 patients with perforating infectious keratitis.

Case summary

Moxifloxacin mixed augmented amniotic membrane transplantations were performed in 2 patients with rapidly deteriorating deep perforated bacterial keratitis. All patients preserved their eyesight. Complete re-epithelization over the amniotic membrane were observed within a month. The corneal surfaces were healed with opacity, and there were no active infectious infiltrations or recurrences for 3 months after application.

Conclusions

Moxifloxacin mixed augmented AMT has proven to be successful both tectonically and physiologically for cases with perforating active bacterial keratitis.

Keywords: Amniotic membrane, Corneal perforation, Corneal ulcer, Fibrin glue, Moxifloxacin

Figures and Tables

Figure 1
Preparation of moxifloxacin mixed fibrin glue.
jkos-53-342-g001
Figure 2
(A) On initial examination, subtotal corneal infectious infiltration with hypopyon and impending corneal perforation was shown. (B) Fourteen days after surgery, the corneal infiltration was remarkably decreased in size and partial epithelial healing was obtained. (C) 4 weeks after surgery, complete re-epithelization was observed. (D) 3 months after surgery, infected and perforated cornea was completely healed.
jkos-53-342-g002
Figure 3
(A) On initial examination, corneal perforation with incarcerated iris and epithelial defects with stromal infiltration was shown. (B) Fourteen days after surgery, epithelial defects were partially restored. (C) 1 month after surgery, complete re-epithelization was observed. (D) 3 months after surgery, infected and perforated cornea was completely healed.
jkos-53-342-g003

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