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Jang, Kim, Lim, Kim, and Sohn: Comparison of 180° and 360° Selective Laser Trabeculoplasty
Original Article
Journal of the Korean Ophthalmological Society

Journal of the Korean Ophthalmological Society 2012; 53(2): 291-296.

Published online: 15 February 2012

DOI: https://doi.org/10.3341/jkos.2012.53.2.291

Comparison of 180° and 360° Selective Laser Trabeculoplasty

Yoon Soo Jang, MD1, Joung Mok Kim, MD2, Tae Hoon Lim, MD3, Hwang Ki Kim, MD1, Yong Ho Sohn, MD, PhD1

1Department of Ophthalmology, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Konyang University, Seoul, Korea.

2Seoul Bright Eye Clinic, Seoul, Korea.

3WooRi Ophthalmic Clinic, Wonju, Korea.

Address reprint requests to Tae Hoon Lim, MD. WooRi Ophthalmic Clinic, #109 Wonil-ro, Wonju 220-956, Korea. Tel: 82-33-746-0212, Fax: 82-33-746-0219, dog408@gmail.com

Received 13 May 2011       Accepted 9 January 2012

Copyright © 2012 The Korean Ophthalmological Society

Abstract

Purpose

To compare the effect and safety of two regimens of Selective Laser Trabeculoplasty (SLT), SLT on 180° of trabecular meshwork and SLT with 100 laser spots on 360° of trabecular meshwork in patients with primary open-angle glaucoma and ocular hypertension.

Methods

In a retrospective clinical study, the authors compared the pressure-lowering effects of SLT in two groups of patients; group 1 (83 patients) received SLT on 180°, group 2 (30 patients) on 360° of trabecular meshwork. The clinical outcome indicators included intraocular pressure (IOP) at one day, one week, one month, two months, three months and six months after SLT, and the anterior chamber reaction at post-laser one day.

Results

There was no statistically significant difference in the IOP reduction between these two regimens after six months. The anterior chamber reactions in the two groups were significantly different (group 1; 0.61 ± 0.64, group 2; 1.25 ± 0.83, p = 0.001). The success rate of group 2 (43.3%) was not different from that of group 1 (31.3%; p = 0.23).

Conclusions

SLT on 180° of trabecular meshwork had a similar effect compared to that of SLT on 360° of trabecular meshwork in terms of IOP reduction. The authors of the present study suggest that 180° SLT is the safest procedure with regard to success rate and complications.

Keywords: Glaucoma, Ocular hypertension, Primary open-angle glaucoma, Selective laser trabeculoplasty

Figures and Tables

Figure 1
Meal IOP changes during follow-up period.
jkos-53-291-g001
Figure 2
Mean IOP reduction percentage during follow-up period.
jkos-53-291-g002
Figure 3
Kaplan-Meier survival curve using definition (failure defined as a need for additional SLT or glaucoma surgery): There were no significant statistical differences between the two groups during the follow-up period. Cumulative survival rate during each period: 1 month -180° 90.4%, 360° 83.3%; 2 months -180° 73.5%, 360° 76.7%; 3 months -180° 66.3%, 360° 73.3%; 6 months -180° 31.3%, 360° 43.3%, p = 0.25 (Log rank [Mantel-Cox] test).
jkos-53-291-g003
Table 1
Patients' demographics
jkos-53-291-i001

Values are presented as mean ± SD or number (%).

POAG = primary open-angle glaucoma; OHT = ocular hypertension; IOP = mean intraocular pressure.

*Two-tailed unpaired t-test; †Chi-square test; ‡Mann-Whitney test.

Table 2
Mean IOP changes after selective laser trabeculoplasty
jkos-53-291-i002

Values are presented as mean ± SD unless otherwise indicated.

IOP = intraocular pressure.

*Unpaired t-test.

Table 3
Number of glaucoma medications after selective laser trabeculoplasty
jkos-53-291-i003

Values are presented as mean ± SD.

*Mann-Whitney test; †Number of medication.

Table 4
Success rate of selective laser trabeculoplasty
jkos-53-291-i004

*IOP decrease at postopertive 6 months >3 mm Hg or >20% comparing baseline without any additional SLT or glaucoma surgery; †Mann-Whitney test.

Table 5
Complication after selective laser trabeculoplasty
jkos-53-291-i005

Values are presented as mean ± SD or number (%).

*Mann-Whitney test; †IOP increase >5 mm Hg.

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