Journal List > J Korean Ophthalmol Soc > v.53(11) > 1009238

Lee, Park, Lee, and Seo: A Case of Ciliary Body Tuberculoma Causing Sclera Melting

Abstract

Purpose

To report a case of ciliary body tuberculoma, which induced scleral melting.

Case summary

A 32-year-old man, who was diagnosed with miliary pulmonary tuberculosis 1 week earlier, presented with a conjunctival injection and mass on his right eye 3 months in duration. On excisional biopsy, melted sclera and exposed uveal tissue were found; acid-fast stain was positive. Two months after anti-tuberculosis treatment, anterior granulomatous uveitis and granuloma formation on the anterior chamber angle developed. A low-dose systemic steroid therapy was added. Six weeks after systemic steroid therapy, anterior uveitis and granuloma on anterior chamber angle disappeared.

Conclusions

We experienced a case of ocular tuberculosis on the ciliary body. A low-dose systemic steroid along with multi-drug anti-tubercular therapy may be an effective treatment of ciliary body tuberculoma.

Figures and Tables

Figure 1
(A) Chest X-ray shows hazziness in both lungs. (B) High resonance CT shows military infiltration in both lungs.
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Figure 2
5×5-mm-sized subconjunctival mass with conjunctival injection.
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Figure 3
(A) Mutton-fat keratic precipitates (red arrows). (B) Grayish-white granuloma on the nasal-side anterior chamber angle.
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Figure 4
(A) Scleral melting area was stable. (B) Peripheral anterior synechia has developed on the previous granuloma site.
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References

1. Sheu SJ, Shyu JS, Chen LM, et al. Ocular manifestations of tuberculosis. Ophthalmology. 2001. 108:1580–1585.
2. Oh YD, Kwak HW. A case of solitary choroidal tuberculoma. J Korean Ophthalmol Soc. 1986. 27:687–691.
3. Ahn JH, Lee CY, Lew HM, Park KH. A case of tuberculosis of lid. J Korean Ophthalmol Soc. 1996. 37:1293–1297.
4. Cho KR, Lee DY. Tuberculous periostitis of the orbit: a case report. J Korean Ophthalmol Soc. 1990. 31:99–103.
5. Kim JI, Lee HS, Lee HK, Yoo JH. A case of conjunctival tuberculosis. J Korean Ophthalmol Soc. 1992. 33:199–202.
6. Shin CH, Lee SN. Atypical ocular and optical coherence tomographic findings with presumed miliary tuberculosis. J Korean Ophthalmol Soc. 2011. 52:107–111.
7. Hong JW, Park YC, Choi GJ. A case of tubeculous neuroretinitis. J Korean Ophthalmol Soc. 2005. 46:1582–1585.
8. Barnes PF, Bloch AB, Davidson PT, Snider DE Jr. Tuberculosis in patients with human immunodeficiency virus infection. N Engl J Med. 1991. 324:1644–1650.
9. Anders N, Wollensak G. [Ocular tuberculosis in systemic lupus erythematosus and immunosuppressive therapy]. Klin Monbl Augenheilkd. 1995. 207:368–371.
10. Ni C, Papale JJ, Robinson NL, Wu BF. Uveal tuberculosis. Int Ophthalmol Clin. 1982. 22:103–124.
11. Helm CJ, Holland GN. Ocular tuberculosis. Surv Ophthalmol. 1993. 38:229–256.
12. Rao NA, Saraswathy S, Smith RE. Tuberculous uveitis: distribution of Mycobacterium tuberculosis in the retinal pigment epithelium. Arch Ophthalmol. 2006. 124:1777–1779.
13. Biswas J, Therese L, Madhavan HN. Use of polymerase chain reaction in detection of Mycobacterium tuberculosis complex DNA from vitreous sample of Eales' disease. Br J Ophthalmol. 1999. 83:994.
14. Biswas J, Kumar SK, Rupauliha P, et al. Detection of mycobacterium tuberculosis by nested polymerase chain reaction in a case of subconjunctival tuberculosis. Cornea. 2002. 21:123–125.
15. Kuruvilla A. Ocular tuberculosis. Lancet. 2003. 361:260–261.
16. Centers for Disease Control. Treatment of tuberculosis. American Thoracic Society, CDC, and Infectious Disease Society of America. >MMWR Recomm Rep. 2003. 52(RR-11):1–77.
17. Rosen PH, Spalton DJ, Graham EM. Intraocular tuberculosis. Eye (Lond). 1990. 4(Pt 3):486–492.
18. Alvarez GG, Roth VR, Hodge W. Ocular tuberculosis: diagnostic and treatment challenges. Int J Infect Dis. 2009. 13:432–435.
19. Gupta V, Gupta A, Rao NA. Intraocular tuberculosis--an update. Surv Ophthalmol. 2007. 52:561–587.
20. Spindler E, Deplus S, Flageul B. [Acute uveitis in reversal reactions]. Acta Leprol. 1991. 7:331–334.
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