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Choi and Shin: Changes in Higher Order Aberration According to Tear-Film Instability Analyzed by Continuous Measurement Using Wavefront
Original Article
Journal of the Korean Ophthalmological Society

Journal of the Korean Ophthalmological Society 2012; 53(8): 1076-1080.

Published online: 17 August 2012

DOI: https://doi.org/10.3341/jkos.2012.53.8.1076

Changes in Higher Order Aberration According to Tear-Film Instability Analyzed by Continuous Measurement Using Wavefront

Si Hwan Choi, MD, Yong Il Shin, MD

Department of Ophthalmology, Chungnam National University School of Medicine, Daejeon, Korea.

Address reprint requests to Si Hwan Choi, MD. Department of Ophthalmology, Chungnam National University Hospital, #282 Munhwa-ro, Jung-gu, Daejeon 301-721, Korea. Tel: 82-42-280-7609, Fax: 82-42-255-3745, shchoi@cnu.ac.kr

Received 31 December 2011       Accepted 25 May 2012

Copyright © 2012 The Korean Ophthalmological Society

Abstract

Purpose

To evaluate the changes of higher order aberration according to tear-film instability measured serially by KR-1W wavefront every second for 10 seconds. The present study also analyzed the relationship between higher order aberration and the tear-film break-up time, Schirmer test, and superficial punctate keratitis.

Methods

The 228 eyes of 114 patients randomly selected from patients who visited hospital were measured once every second for 10 seconds after eye blinking by continuous measurement using wavefront.

Results

Higher order aberration increased overtime, and the higher order aberration value measured at the tenth second subtracted from the value of the first second was statistically significant (p = 0.004). In addition, the increment in higher order aberration between 9 seconds and 10 seconds was statistically significant (p = 0.01). The group of patients with a tear-film break-up time less than 6 seconds showed the greatest changes when measuring the higher order aberration difference value between the tenth and first seconds, which was statistically significant (p = 0.002). The group of patients where the Schirmer test results were longer than 10 millimeters and who had superficial punctate keratitis showed the greatest statistically significant changes when measuring the difference in higher order aberration values between the tenth and first seconds (p = 0.008, p = 0.005, respectively).

Conclusions

Analysis of higher order aberration by wavefront could be useful in cases of decreased optical quality, diagnosis and evaluation of treatment in dry eye syndrome.

Keywords: Dry eye syndrome, Higher order aberration, KR-1W, Wavefront

Figures and Tables

Figure 1
Changes in higher order aberration over time.
RMS = root mean square.
jkos-53-1076-g001
Table 1
Demographics
jkos-53-1076-i001

Values are presented as mean ± SD or number unless otherwise indicated.

SPK = superficial punctate keratitis.

Table 2
Mean values and changes in higher order aberration at 1 and 10 seconds in each group classified according to the BUT
jkos-53-1076-i002

HOA = higher order aberration.

Table 3
Mean values and changes in higher order aberration at 1 and 10 seconds in each group classified according to the Schirmer test
jkos-53-1076-i003

HOA = higher order aberration.

Table 4
Mean values and changes in higher order aberration at 1 and 10 seconds in each group classified according to the presence of superficial punctate keratitis
jkos-53-1076-i004

SPK = superficial punctate keratitis; HOA = higher order aberration.

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