Successful Removal of Apocrinehydrocytoma Using Indocyanine Green and Sodium Hyaluronate

Boyun Kim; Nam Yeo Kang

doi:10.3341/jkos.2011.52.8.994

Journal List > J Korean Ophthalmol Soc > v.52(8) > 1009112

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Kim and Kang: Successful Removal of Apocrinehydrocytoma Using Indocyanine Green and Sodium Hyaluronate

Original Article

J Korean Ophthalmol Soc 2011;52(8):994-998.

Published online: 7 September 2011

DOI: https://doi.org/10.3341/jkos.2011.52.8.994

Successful Removal of Apocrinehydrocytoma Using Indocyanine Green and Sodium Hyaluronate

Boyun Kim, MD, Nam Yeo Kang, MD

Department of Ophthalmology, Bucheon St. Mary's Hospital, The Catholic University of Korea College of Medicine, Bucheon, Korea

Address reprint requests to Nam Yeo Kang, MD Department of Ophthalmology, The Catholic University Bucheon St. Mary's Hospital #2 Sosa-dong, Wonmi-gu, Bucheon 420-717, Korea Tel: 82-32-340-2125, Fax: 82-32-340-2661, E-mail: nyeokang@hanmail.net

Received 2 October 2010 Revised 18 February 2011 Accepted 29 April 2011

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report a new modified method using a mixture of sodium hyaluronate and indocyanine green solution to facilitate the complete removal of a large conjunctival cyst.

Case summary

Two patients with a large conjunctival cyst on the bulbar conjunctiva were treated. In order to achieve complete removal, a mixture of 1% sodium hyaluonate and indocyanine green solution was injected through a 27-G needle into the cyst. The procedure provided excellent visualization of the cyst boundaries while maintaining cyst integrity allowing for an easy and complete resection. Apocrine hidrocystoma and a simple retention cyst were confirmed on histopathologic examination, respectively.

Conclusions

During the removal of a large cyst, injecting a mixture of sodium hyaluronate and indocyanine green is effective in delineating the cyst capsule while preserving its integrity, thus aiding in the complete removal of the cyst wall.

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Keywords: Conjunctival cyst, Indocyanine green, Sodium hyaluronate

References

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Figure 1.

(A) 6×5 mm-sized large conjunctival cyst is seen in the bulbar conjunctiva of the right eye.(B) The cyst margin are clearly visible through the conjunctiva after stained with a mixture of sodium hyaluronate and indocyanine green solution. (C, D) Successful removal of the conjunctival cyst with delineated capsule and preserved integrity.

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Figure 2.

Double layered lining of apocrine hidrocytoma (H&E stain, ×40) (A), consisting of large columnar cells with eosinophilic cytoplasm with luminal decapitation secretion in the inner layer and flat myoepithelial cells in the outer layer (H&E stain, ×100).(B) Arrows indicate PAS-positive, diastase-resistant granule on the apical surfaces of the inner layer (PAS stain, ×100).

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Figure 3.

(A) 6×4 mm-sized large conjunctival cyst is seen in the medial conjunctiva adjacent to the caruncle of the right eye. (B) The cyst is stained using a mixture of sodium hyaluronate and indocyanine green solution. (C) Succesful removal of the conjunctival cyst with delineated capsule and preserved integrity. (D) A solitary uniocular cyst is lined by non-keratinizing cuboidal epithelium. Goblet cells are often included (H&E stain, ×20).

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