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Abstract
Purpose
To evaluate the differences in corneal endothelial cell density in patients undergoing intraocular lens insertion at 2 different sequences during the triple procedure.
Methods
The present retrospective study divided 37 eyes of 37 patients and into 2 groups: trephination, phacoemulsification and intraocular insertion, followed by graft suturing (20 eyes, Group I), and trephination, phacoemulsification, graft suturing leaving 3 mm gap, followed by intraocular lens insertion and suturing of the gap (17 eyes, Group II). Intraocular pressure, corneal thickness, and endothelial cell density were measured for 3 months postoperatively.
Results
No significant difference in intraocular pressure between the 2 groups (p = 0.14) was observed. However in Group II, the mean corneal thickness showed a greater decrease (p = 0.02) during the 3 months following surgery, and the mean corneal endothelial cell density in this group was higher at 1, 2, and 3 months postoperatively than that of Group I (p = 0.01, 0.02 and 0.04 respectively). There were no significant difference in the rate of endothelial cell loss during the post-operative period between the 2 groups.
References
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Figure 2.
Comparison of preoperative and postoperative corneal endothelial cell density in Group I and II.
Table 1.
Clinical characteristics in Group I and II
| | Group I | Group II | ‡ p-value |
|---|---|---|---|
| Recipient | | | |
| Age (mean ± SD, yr) | 55.3 ± 10.9 | 58.2 ± 12.1 | 0.23 |
| Sex (M/F) | 11/9 | 10/7 | |
| Laterality (OD/OS) | 7/13 | 9/6 | |
| Follow-up period (mean ± SD, mon) | 7.4 ± 3.1 | 7.9 ± 3.9 | 0.10 |
| Donor | | | |
| Age (mean ± SD, yr) | 63 ± 7.8 | 64 ± 7.2 | 0.17 |
| Trephine size (mean ± SD, mm) | 7.68 ± 0.45 | 7.72 ± 0.42 | 0.08 |
| * CD (mean ± SD, cells/mm2) | 2562 ± 299 | 2512 ± 315 | 0.19 |
| † CT (mean ± SD, um) | 641 ± 33 | 656 ± 40 | 0.14 |
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