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Abstract
Purpose
To evaluate the effect of epinephrine on pupil size in reconstruction of an orbital wall fracture.
Methods
The authors of the present study describe 27 patients (27 eyes) who had reconstruction of an orbital wall fracture from January to July of 2009. Patients were divided into two groups according to the use of epinephrine during surgery. Preoperative and postoperative pupil sizes, operation times, and epinephrine dosages were collected.
Results
Preoperative pupil sizes were 1.80 ± 0.37 mm, 1.74 ± 0.36 mm and postoperative pupil sizes were 1.97 ± 0.43 mm (p = 0.042), 2.18 ± 0.52 mm (p = 0.003) in the group with of epinephrine and the group without epinephrine, respectively. Postoperative pupil size significantly increased in all groups. However, no significant difference was found regarding change in pupil size after surgery (p = 0.258). In the group with epinephrine, change in pupil size did not show a significant association with operation time (p = 0.228), nor did change in pupil size and epinephrine dosage (p = 0.922).
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Figure 1.
The comparison that displays the change in pre- and post-operative pupil size (Repeated measures ANOVA, p = 0.258). Inj. = epinephrine injection.
Figure 2.
The change in pupil size by operation time in epinephrine injection group (Linear regression, p = 0.228).
Figure 3.
The change in pupil size by amount of injection in epinephrine injection group (Linear regression, p = 0.922).
Table 1.
Demographic characteristics of patients
| Age (yr) | Male | Female | Total |
|---|---|---|---|
| 1-20 | 7 | 3 | 10 |
| 21-40 | 9 | 2 | 11 |
| 41-60 | 4 | 1 | 5 |
| 61-80 | 1 | 0 | 1 |
| Total | 21 | 6 | 27 |
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