Bilateral Simultaneous Acute Angle Closure Glaucoma Following Sexual Intercourse Aided by Sildenafil Citrate

Won June Lee; Mincheol Seong

doi:10.3341/jkos.2011.52.9.1123

Journal List > J Korean Ophthalmol Soc > v.52(9) > 1008892

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Lee and Seong: Bilateral Simultaneous Acute Angle Closure Glaucoma Following Sexual Intercourse Aided by Sildenafil Citrate

Original Article

J Korean Ophthalmol Soc 2011;52(9):1123-1127.

Published online: 7 September 2011

DOI: https://doi.org/10.3341/jkos.2011.52.9.1123

Bilateral Simultaneous Acute Angle Closure Glaucoma Following Sexual Intercourse Aided by Sildenafil Citrate

Won June Lee, MD, Mincheol Seong, MD

Department of Ophthalmology, Hanyang University College of Medicine, Guri, Korea

Address reprint requests to Mincheol Seong, MD Department of Ophthalmology, Hanyang University Guri Hospital #249-1 Gyomun-dong, Guri 471-701, Korea Tel: 82-31-560-2354, Fax: 82-31-564-9479, E-mail: goddns76@hanmail.net

Received 27 December 2010 Revised 17 March 2011 Accepted 5 June 2011

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The authors of the present study report a case of bilateral simultaneous acute angle closure glaucoma following sildenafil citrate-aided sexual intercourse.

Case summary

A 63-year-old man visited the emergency department with sudden onset of bilateral ocular pain and blurred vision. The patient had taken 50 mg sildenafil citrate followed by sexual intercourse. His visual acuity on presentation was 0.3 in the right eye and 0.5 in the left eye. Intraocular pressure (IOP) was 54 mm Hg and 46 mm Hg in the right and left eye, respectively. Anterior chamber depths were shallow and angles were closed on gonioscopy in both eyes. The patient was treated with ocular hypotensive medication and subsequently managed with bilateral YAG laser peripheral iridotomies. During the 13 months of follow-up, there was no recurrent angle closure attack and IOPs were well-controlled.

Conclusions

The mechanism of bilateral angle closure glaucoma caused by sildenafil citrate is not proven. Those who are predisposed towards developing angle-closure glaucoma may be at risk when having sexual intercourse aided by sildenafil citrate.

Keywords: Anterior chamber depth, Bilateral acute angle-closure, Intraocular pressure, Sildenafil citrate, YAG laser peripheral iridotomy

References

1. Laties A, Zrenner E. Viagra (sildenafil citrate) and ophthalmology. Prog Retin Eye Res. 2002; 21:485–506.

2. Cordell WH, Maturi RK, Costigan TM, et al. Retinal effects of 6 months of daily use of tadalafil or sildenafil. Arch Ophthalmol. 2009; 127:367–73.

3. Yajima T, Yajima Y, Koppiker N, et al. No clinically important effects on intraocular pressure after short-term administration of sildenafil citrate (Viagra). Am J Ophthalmol. 2000; 129:675–6.

4. Ramasamy B, Rowe F, Nayak H, et al. Acute angle-closure glaucoma following sildenafil citrate-aided sexual intercourse. Acta Ophthalmol Scand. 2007; 85:229–30.

5. Lachkar Y, Bouassida W. Drug-induced acute angle closure glaucoma. Curr Opin Ophthalmol. 2007; 18:129–33.

6. Craig JE, Ong TJ, Louis DL, Wells JM. Mechanism of top-iramate-induced acute-onset myopia and angle closure glaucoma. Am J Ophthalmol. 2004; 137:193–5.

7. Trittibach P, Frueh BE, Goldblum D. Bilateral angle-closure glaucoma after combined consumption of “ecstasy” and marijuana. Am J Emerg Med. 2005; 23:813–4.

8. Kee C, Kaufman PL, Gabelt BT. Effect of 8-Br cGMP on aqueous humor dynamics in monkeys. Invest Ophthalmol Vis Sci. 1994; 35:2769–73.

9. Paris G, Sponsel WE, Sandoval SS, et al. Sildenafil increases ocular perfusion. Int Ophthalmol. 2001; 23:355–8.

10. Harris A, Kagemann L, Ehrlich R, et al. The effect of sildenafil on ocular blood flow. Br J Ophthalmol. 2008; 92:469–73.

Figure 1.

B-scan ultrasonography was done and there were no signs of ciliochoroidal detachment.

Figure 2.

Bilateral YAG laser peripheral iridotomies were performed and the photograph shows patent iridotomies.

Figure 3.

A digital red-free fundus photographs were taken 3 weeks after his first visit. Localized inferior temporal retinal nerve fiber layer (RNFL) defects are seen in the left eye (white arrow).

TOOLS

Similar articles