Bilateral Serous Retinal Detachment Associated With Alport's Syndrome

Young Bin Song; Sung Pyo Park

doi:10.3341/jkos.2010.51.3.463

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Song and Park: Bilateral Serous Retinal Detachment Associated With Alport's Syndrome

Original Article

J Korean Ophthalmol Soc 2010;51(3):463-468.

Published online: 25 September 2010

DOI: https://doi.org/10.3341/jkos.2010.51.3.463

Bilateral Serous Retinal Detachment Associated With Alport's Syndrome

Young Bin Song, MD, Sung Pyo Park, MD

Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea

Address reprint requests to Sung Pyo Park, MD Department of Ophthalmology, Kangdong Sacred heart Hospital, Hallym University College of Medicine #445 Gil-dong, Gangdong-gu, Seoul 134-701, Korea Tel: 82-2-2224-2274, Fax: 82-2-470-2088, E-mail: sungpyo@hananet.net

Received 24 November 2008 Accepted 1 April 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

To report a case of bilateral serous retinal detachment associated with Alport's syndrome that resolved following intensive blood pressure control and electrolyte imbalance correction.

Case summary

A 50-year-old male patient presented with bilateral lenticonus and bilateral serous retinal detachment. Bilateral serous retinal detachment with retinal flecks characteristic of Alport's syndrome appeared along with the development of chronic renal failure and hypertension. The following kidney biopsy revealed Alport's syndrome. After 14 days, the serous detachment resolved and vision recovered following intensive blood pressure control and electrolyte imbalance correction fundus and FA results were nearly normal.

Conclusions

In this case, bilateral serous retinal detachment in Alport's syndrome resolved with intensive blood pressure control and electrolyte imbalance correction. To the author's knowledge, this is the first case in South Korea with documentation of the onset and resolution of bilateral serous retinal detachment in Alport's syndrome.

Keywords: Alport's syndrome, Serous retinal detachment

References

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Figure 1.

Bilateral anterior lenticonus was shown on slit-lamp examination.

Figure 2.

The typical pictures of a drop of oil in water “oil-globule”.

Figure 3.

Bilateral perimacular flecks with serous retinal detachment were shown.

Figure 4.

Bilateral serous retinal detachment was found on OCT.

Figure 5.

The following kidney biopsy revealed it to be Alport's syndrome; Stars indicate, from above, diffuse foot process effacement, compressed glomerular capillary lumina and GBMs increased in thickness and irregular wrinkled contours, respectively.

Figure 6.

The serous retinal detachment resolved and the vision recovered following intensive blood pressure control and electrolyte imbalance correction.

Figure 7.

Fluorescein angiogram findings were nearly normal after the serous retinal detachment resolved.

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