Journal List > J Korean Ophthalmol Soc > v.51(3) > 1008770

Roh, Kim, and Yu: A Case of Coats' Disease Accompanying A Retinal Macrocyst

Abstract

Purpose

To report a case of laser photocoagulation treatment for the patient of Coats' disease accompanying a retinal macrocyst.

Case summary

A three-year-old boy visited the hospital whose chief complaint was visual acuity decrease of his left eye. Fundus examination showed macular scar, foveal hard exudates and inferior retinal cystic lesion in his left eye. Two months later, examination under anesthesia (EUA) and fluorescein angiography (FAG) was performed. The results revealed inferior retinal macrocyst, nasal avascular retina and telangiectasia around the retinal macrocyst. Laser photocoagulation was performed around the retinal macrocyst and at the nasal avascular retina. One year after the laser photocoagulation, retinal macrocyst did not further progress and the retina was stabilized.

Conclusions

Laser photocoagulation was done around the retinal macrocyst and at the nasal avascular retina of the Coats' disease accompanying a retinal macrocyst and the lesions did not further progress and the retina was stabilized.

References

1. Reese AB. Telangiectasis of the retina and Coats' disease. Am J Ophthalmol. 1956; 42:1–8.
crossref
2. Choi SY, Yu YS. Treatment and clinical results of Coats' disease. J Korean Ophthalmol Soc. 1999; 40:2190–7.
3. Rubin MP, Mukai S. Coats' disease. Int ophthalmol clin. 2008; 48:149–58.
crossref
4. Shields JA, Shields CL, Honavar SG, et al. Classification and management of Coats disease. The 2000 Proctor Lecture. Am J Ophthalmol. 2001; 131:572–83.
crossref
5. Jones JH, Kroll AJ, Lou PL, Ryan EA. Coats' disease. Int Ophthalmol Clin. 2001; 41:189–98.
crossref
6. Shields JA, Shields CL, Honavar S, Demirci H. Coats' disease. Clinical variations and complications of Coats' disease in 150 cases. The 2000 Sanford Gifford Memorial Lecture. Am J Ophthalmol. 2001; 131:561–71.
7. Imre G. Coats' disease. Am J Ophthalmol. 1962; 54:175.
8. Tolentino MJ, McLeod DS, Taomoto M, et al. Pathologic features of vascular endothelial growth factor-induced retinopathy in the nonhuman primate. Am J Ophthalmol. 2002; 133:373–85.
crossref
9. Tolentino MJ, Miller JW, Gragoudas ES, et al. Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate. Ophthalmology. 1996; 103:1820–8.
crossref
10. Su CY, Chen MT, Wu WS, Wu WC. Concentration of vascular endothelial growth factor in the subretinal fluid of retinal detachment. J Ocul Pharmacol Ther. 2000; 16:463–9.
crossref
11. Sun Y, Jain A, Moshfeghi DM. Elevated vascular endothelial growth factor levels in Coats disease: rapid response to pegaptanib sodium. Graefes Arch Clin Exp Ophthalmol. 2007; 245:1387–8.
crossref
12. Venkatesh P, Mandal S, Garg S. Management of Coats disease with bevacizumab in 2 patients. Can J Ophthalmol. 2008; 43:245–6.
crossref
13. Alvarez-Rivera LG, Abraham-Marin ML, Flores-Orta HJ, et al. Coats' disease treated with bevacizumab. Arch Soc Esp Oftalmol. 2008; 83:329–31.
14. Couvillion SS, Margolis R, Mavrofjides E, et al. Laser treatment of Coats' disease. J Pediatr Ophthalmol Strabismus. 2005; 42:367–8.
crossref

Figure 1.
Fundus photograph of the left eye taken on the day of the first visit. (A) Large retinal cystic lesion at the inferior to the inferotemporal major arcade is observed. (B) Foveal hard exudates and macular scar changes are also observed.
jkos-51-453f1.tif
Figure 2.
Ultrasonography of the left eye taken on the day of the first visit. Cystic lesion and intracystic hypoechoic signals are observed.
jkos-51-453f2.tif
Figure 3.
Fluorescein angiogram before the laser photocoagulation during the examination under anesthesia shows retinal macrocyst (A), telangiectatic vessel around the macrocyst and nasal avascular area (B).
jkos-51-453f3.tif
Figure 4.
Fundus photograph taken after the laser photocoagulation during the examination under anesthesia. Laser photocoagulation treatment was performed around the macrocyst (A) and at the nasal avascular area (B).
jkos-51-453f4.tif
Figure 5.
Fundus photograph taken one year after the laser photocoagulation. Retinal macrocyst (A) and nasal avascular area (B) are not progressed and stabilized.
jkos-51-453f5.tif
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