Abstract
Purpose
To evaluate the long-term results of the application of a mixed solution of hyaluronate and sodium carboxymethlycellulose (HACMC, Guardix-sol) intraoperatively in endonasal dacryocystorhinostomy (Endo-DCR).
Methods
In this retrospective randomized controlled study, Endo-DCR and silicone tube intubation were performed on 83 eyes of 83 patients who were diagnosed with nasolacrimal duct obstruction. In group A (40 patients, 40 eyes), HACMC was applied to the osteotomy site in the nasal cavity after standard Endo DCR procedure. In group B (43 patients, 43 eyes), a standard Endo-DCR procedure was performed without HACMC. The results for the two groups were evaluated by asking patients about the tearing condition and examining the patency of irrigation, complications, and related treatment.
Results
There were no statistically significant differences in age, sex, silicone tube insertion duration, or mean follow-up time between the two groups. The primary success rates of the group A and the group B were 87.5% (35/40) and 81.4% (35/43), respectively. The final success rates after the revisonal surgery were 92.5% (37/40) and 86.0% (37/43), respectively, and there were no statistically significant differences between the two groups (P=0.348, Fisher's exact test).
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Figure 1.
0.25% sodium hyaluronate + 0.49% carboxymethylcellulose (Gardix-sol, Hanmi MediCare, Korea).
![jkos-51-159f1.tif](/upload/SynapseXML/0035jkos/thumb/jkos-51-159f1.gif)
Table 1.
Demographic data of patients
Table 2.
Preoperative diagnosis in two groups
|
Number of cases (%) |
|
---|---|---|
Group A (n=40) | Group B (n=43) | |
Nasolacrimal duct obstruction | 22(55.5%) | 25(58.1%) |
Chronic dacryocystitis | 16(40.0%) | 17(39.5%) |
Previous failed DCR* | 2(5.0%) | 1(2.3%) |
Table 3.
Total success rate of DCR
|
Number of case (%) |
|
---|---|---|
Group A (n=40) | Group B (n=43) | |
Primary Success* Rate | 87.5%(35/40) | 81.4%(35/43) |
Final Success Rate | 92.5%(37/40) | 86.0%(37/43) |