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Abstract
Purpose
To report a case of acyclovir-induced acute renal failure (ARF) suspected as acute retinal necrosis syndrome.
Case summary
The authors report a 55-year-old male patient who presented with left eye visual disturbance due to suspected acute retinal necrosis syndrome. Non-oliguric ARF developed after the infusion of intravenous acyclovir (850 mg every 8 hours). The patient did not show any uremic symptoms or signs. The crystal was not discovered in the urine. After stopping the acyclovir infusion and hydration, acyclovir-induced ARF was reversed.
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Figure 1.
Initial fundus photograph of the left eye shows retinal necrosis (arrowhead) with retinal hemorrhages (arrowheads), obscured by dense vitreous opacity (A). After 3 months of the initial diagnosis, the vitreous inflammation and necrotic retinal lesions resolved almost completely, leaving behind ischemic retina with occluded retinal vessels inferotemporally (B).
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